Pregnancy: who is at risk? Highlight the risk groups of pregnant women in the antenatal clinic for obstetric and perinatal pathology

However, one should turn to these methods only after carefully weighing all the pros and cons. The probability of miscarriage when taking chorionic villi is 1:100, and when taking amniotic fluid - 1:200. If a woman's risk of fetal damage is greater than the risk of pregnancy loss during diagnostic tests (for example, 1:80), then it is rational to conduct them with the consent of the woman. If the risk of fetal damage is less than the risk of pregnancy loss, the doctor has no right to insist on the use of an invasive diagnostic test. For example, a screening result of 1:300 is a 0.3% chance of fetal damage, which is actually a low rate. At the same time, when collecting lint...


How are examinations for genetic abnormalities and malformations carried out: ultrasound, amniocentesis and others


Are flights dangerous during pregnancy, what month is it better to organize a trip, the rules for "transporting" the belly, and other useful answers to disturbing questions. Pregnancy is shrouded in many different prejudices. Grandmother says that you can’t have a haircut, mom says that you can’t buy a dowry for a baby in advance; we reject thousands of nonsense instructions and continue to lead our usual rich life, continue to work ...
... However, there is no scientific evidence for it. Of course, premature births are not uncommon, they can occur on earth. But it is in the air that there will be no resuscitation for children, a team of doctors and the opportunity to provide qualified assistance. You can find out the risk of preterm birth on an ultrasound by measuring the length of the cervix. Many airlines are imposing restrictions on the flight of women who have a high chance of experiencing the joy of motherhood right on the plane. These include late-term pregnant women, women with multiple pregnancies, and those who already have a history of preterm birth. 2. Lack of oxygen During the flight in the cabin of the aircraft, the oxygen concentration ...


Discussion

I accepted for myself the fact that if the baby has Down syndrome it is better to know about it in advance. It was just at my first screening. And another indisputable fact is that in such suspicious cases it is better to find out everything in advance as accurately as possible, to accept it, to find the strength in yourself to accept it. Raising such a child in the future will be very difficult. Prenetix, by the way, is able to identify a similar problem (and many others) even in the early stages, I did it with them, I remember how everything went. Safe and results are fast. Thank God, at least everything turned out to be in order in the end.

Screening

26.04.2017 22:19:37, LEILA

Features of the course of diabetes mellitus in pregnant women. Symptoms of diabetes. Treatment of diabetes during pregnancy.

Discussion

I have been suffering from diabetes for 14 years (I got sick at the age of 19). She gave birth to her first child quite a bit prematurely, weighing 3.8 kg. Now pregnant with a second. Glycosylated hemoglobin - 6.2. In the first pregnancy, even 6.1. I generally tend to low sugar as a response to injected insulin. But without it, in any way - very high sugar. Why am I? If diabetes is well compensated, then normal children with normal weight are born. The article writes as if all pregnant women with diabetes have children over 4.5 kg., Edema, etc. Not true! I have a very smart, healthy son, my daughter is also with quite normal weight. Should be born soon. So if you keep diabetes under control, everything will be fine! By the way, I have type 1 diabetes, on insulin. And I eat sweets almost as much as I want. I just clearly and often enough control the level of sugar in the blood and reduce high sugar immediately. But without fanaticism. Gipy - also not autumn good (too low blood sugar). True, the doctor tells me that low blood sugar in the mother's blood does not affect the baby, it affects high if it is not lowered by insulin for a long time. All health and more optimism!

08/08/2018 15:52:48, Irina Khaze

I was diagnosed with high blood sugar at 35 weeks. This analysis was done because of my large weight gain (22 kg). There is no protein in the urine, only edema, pressure is normal. What happened with me? Is it diabetes? Can a woman gain that much weight without being diabetic? Everyone says I have a big belly. I have pain in the pubic area and increased uterine tone. But thank God I have a long term and I feel the movements of the fetus. This gives at least some hope that he will be born alive. I'm already sick of going to the doctors, then they are not in place, then there is a large record, etc. And in general they are rude to me. Is it okay to yell at a woman just because she's overweight? Especially for a pregnant woman. Like it's my fault! They put me on a diet, where to eat the last time no later than 18.00. So what? I got out of the hospital and still eat what I want. The only thing is that I drink sugar-reducing tea before meals. Why do doctors love to prescribe diets and insulin so much, completely forgetting about herbal medicine? And further. Insulin must be produced by the pancreas. So it would be nice to write the reasons why insulin itself is not produced. Is it really that hard?

01.11.2007 00:30:15, Lana

How to avoid the threat?

Discussion

Please help. I'm 7 weeks pregnant. And I've had brown discharge for 2 days already. I'm drinking dufaston. I'm afraid of losing my baby. What should I do?

06/09/2016 19:50:30, Aidana

Hello, I am 15 weeks pregnant, I was already in bed with preservation, now I am worried about pain in my back and lower abdomen, I still have erosion, purulent discharge and something else. I don't know what to do, please help me. Thanks

05/04/2008 10:45:18, Didara

Treatment of SARS during pregnancy
... Children, the elderly and pregnant women are at increased risk. According to different authors, SARS occur in pregnant women with a frequency of 55 to 82%. What is SARS Acute respiratory infections is the common name for a number of infectious diseases caused by viruses and bacteria and occurring with symptoms of damage to the mucous membranes of the respiratory tract (nose, larynx, trachea, bronchi), and sometimes with ...

Discussion

Well, this is a common topic of SARS. It's just that pregnant women should not be treated with antibiotics, but with something simple, such as hot milk, honey, tea with lemon. It's easier. and everything will pass

Drinking homeopathy is a waste of money. It does not contain active ingredient molecules, only lactose. If there is a lactase deficiency, it will also swell. The disease itself will pass from 2 to 7 days. After does not mean due to. You might as well eat a cucumber and get well. As for the danger to the fetus, it probably makes sense to voice in which trimester this happened ...

25.09.2018 22:20:45, NinaVa


Discussion

"The frequency of examinations should not be less than 10-12 times." A scarecrow has appeared in our city: that if the number of entries in the dispensary book (exchange card) is less than 12, then they will not issue a birth certificate :) On this occasion, many women, like me, who, due to constant hospitalization, say, by 22 Weeks only 2 entries, somewhat puzzled. In the regiment I was reassured that this was invented by bureaucrats who had little idea of ​​the process of observing women. After all, there are those who are immediately hospitalized until the birth and they will have only a couple of epicrises and 1 entry in the exchange office.


Ideally, this doctor's office should be visited during pregnancy preparation. If future parents have not done this, then the couple should turn to genetics in cases where there is an increased risk of having a child with a hereditary pathology. We list the circumstances that may be the reason for seeking advice from a geneticist. the birth of a child with hereditary diseases ...
...After talking with future parents and receiving test results, the geneticist determines the degree of genetic risk for each particular family. Genetic risk is the probability of occurrence of a certain hereditary pathology in the person who applied for a consultation or in his descendants. It is determined by calculations based on the analysis of genetic patterns, or using the data of the analyzes performed. The ability to calculate the genetic risk depends mainly on the accuracy of the diagnosis and the completeness of the genealogical data (data on the families of the spouses), so the couple must ...

Discussion

Hello, please help me figure it out. They put the risk for Down syndrome 1: 146. KTP 46 mm, TVP 2.0 mm. Visualization of the nasal bone +. There are no features of the anatomy of the fetus. Chorion: localization along the anterior wall of the uterus. pregnancy. High risk with these indicators of fetal disease? Missed pregnancy at 5 weeks in 2015

10/25/2016 11:22:59 PM, Valeria

Hello. My husband and I are planning to undergo a genetic examination before conception, because. my husband's older brother has some kind of mental illness. Their parents are stubbornly silent and do not want to talk about this topic, and find out that it is not possible with the elder, and I am frankly afraid that because of such a close relationship this problem may affect us ... Please tell me where in Moscow you can to pass or take place such inspection, and whether probably in general to define or determine hereditary it unknown mental disease? Thank you very much in advance!
Good afternoon! I found this appeal in your blog, and I have a similar question. I will wait for an answer!

03/21/2016 02:01:41 PM, Maria

The causative agents of childhood infections (more often these are viruses) have a high ability to cause disease and are transmitted by airborne droplets from a sick person to a healthy person when sneezing, coughing, breathing. It should be noted right away that the risk of contracting childhood infections during pregnancy is not higher than in non-pregnant women. However, the manifestations of such acute infectious diseases during pregnancy have a number of features: firstly, in most cases they proceed non-specifically, which makes diagnosis difficult; secondly, the causative agents of childhood infections (viruses) penetrate the placenta into the blood of the fetus, so they can disrupt the development of tissues and or...

Discussion

Hello! I read your article about childhood infectious diseases during pregnancy. Interested in information about whooping cough during B? Could you tell something? I got whooping cough at 8 weeks B, while they found out that two weeks had passed with me, at 10 weeks B, I drank Vilprafen, the doctors reassure me that nothing should affect the child, but I'm still very scared for the baby. It’s not possible to consult with various infectious disease specialists (((According to ultrasound and screenings, everything is fine, now it’s 27 weeks B. It’s still very scary for the baby, he poor has suffered before he was born !!! And another question about scarlet fever ... for the older child in the garden (not in our group yet!) quarantine for scarlet fever, I'm afraid to take him to the garden (even more because of my pregnancy), leave him at home or take him to the garden? maybe scarlet fever at 27 weeks B? I can't take a second infectious disease in B!! Thanks in advance for your reply!


During this period of the life of a thrombus, there is a very high probability of a part of it being torn off, which can be transferred with the blood flow to the chambers of the heart or, most dangerously, to the pulmonary arteries. Blockage of even small branches of the pulmonary artery can lead to the exclusion of part of the lung from breathing, which is a direct threat to life. During pregnancy, vein thrombosis is not uncommon, therefore, at this time, the efforts of doctors are aimed at identifying the risk of thrombosis, prescribing preventive measures. However, the following situation often develops: the birth went well; it would seem that everything is over, the danger has passed, no more prevention is required. But it is at this time that the risk of late complications of pregnancy and childbirth of postpartum thrombosis increases. Causes of thrombosis First of all, r...


Why is gestational diabetes dangerous during pregnancy?


Where does fibroid come from and how to treat it?
...Figures and facts 4% of pregnancies occur against the background of uterine fibroids. At the same time, in 50-60% of cases, slight changes in the size of myomatous nodes are observed: according to various scientists, 22-32% of pregnant women have their growth, and 8-27% - a decrease. During pregnancy occurring against the background of uterine fibroids, complications are observed in 10-40%. These are abortion, premature birth, fetal damage and malnutrition (stunting). Yet most pregnancies with uterine fibroids proceed normally. Quite often, the nodes prevent the proper contraction of the uterus during childbirth, so about half of pregnant women with uterine myoma are sent for caesarean section.


What is placental insufficiency - treatment and prevention


Let's see if this is true, shall we? Repeated births with a scar on the uterus mostly pass without any special complications. However, in 1-2% of a hundred such births may end in partial or complete rupture of the suture. Other studies have estimated the chance of uterine rupture at 0.5%, provided that labor was not initiated medically. Also, one of the factors that increase the risk of rupture, according to some reports, is the age of the mother and too short an interval between pregnancies. The divergence of the suture on the uterus during repeated births is a potentially dangerous condition for both the mother and the child, and requires immediate surgical intervention. Fortunately, uterine rupture, if the operation was performed with a horizontal incision in its lower segment, is a rather rare phenomenon, which occurs in less than 1% of women giving birth ...



If there is no certainty that a weakened child will endure birth stress, a caesarean section is preferred. Prevention of FPI It is necessary to think about the well-being of the unborn child even before pregnancy. It must be remembered that abortions, injuring the uterus, can later lead to violations of the uteroplacental circulation. During pregnancy, it is better to strongly refrain from smoking and drinking alcohol, contact with toxic substances and radiation sources - especially in the early stages of pregnancy, when the placenta is forming. It is necessary to timely (and better - in advance) treat infectious diseases and possible foci of infection, such as carious teeth or chronic tonsillitis. To all expectant mothers without exception...
... It is necessary to treat infectious diseases and possible foci of infection, such as carious teeth or chronic tonsillitis, in a timely manner (or better, in advance). All expectant mothers, without exception, are advised to take multivitamin preparations for pregnant women. Sometimes high-risk pregnant women (too young; women over 30 expecting their first child; suffering from chronic diseases; who have given birth to small children in the past; with long intervals between pregnancies) are recommended courses of drug prevention of FPI for up to 12 weeks, 20-23 weeks and 30-32 weeks, which include vasodilators and vitamins. Separated Consequences How ...

Discussion

Very informative. They did CTG for me, but we were told the scores (from 0 to 10), and not the heart rate of the child.
Also: there are rare cases when the cycle lasts not the "usual" 28-36 days, but more, then you have to prove that you are "not a camel". My two babies were given IUGR 2 weeks behind. And according to the ultrasound in dynamics and according to the CTG, everything was also in dynamics, but the ultrasound showed a delay just for my two weeks and for some reason the doctor did not want to hear about my own even 43 day cycle. In general, the babies were born on their due date, and not set for a 28-day cycle (I don’t remember what this lag is called, but in general, this is an imaginary lag). And although the babies were born with a weight of exactly 3.0 kg each, there was no IUGR. But, my case is an exception :).

Every time we decide to get pregnant, we take a certain risk. This risk can be eliminated and unavoidable. Unavoidable risks include ACCIDENTAL genetic changes and some chronic diseases. The area of ​​avoidable risks is much wider. Pre-pregnancy studies of the state of your body will in many cases significantly (very significantly!) Reduce the risk of an unfavorable outcome. Here we are talking about miscarriages, and missed pregnancies, and about birth ...

Discussion

There has become a lot of information, it must be laid out separately and categorized.

I started hosting www.planirovanie.hut2.ru, while it is not available, but by Monday, I hope, I will start uploading it.

Preparation for pregnancy. What should be included in the consultation for a planned pregnancy:

Folic acid prescription: 400 mcg per day. For diabetes and epilepsy, 1 mg per day, 4 mg for women with children with neural tube defects.

ethnic history.

Family history.

Tests for HIV, syphilis.

If necessary, immunization against hepatitis B, rubella, chickenpox.

Discussion of ways to prevent infection with CMV, toxoplasmosis, parvovirus B19.

Discussion of factors harmful to pregnancy in everyday life (pesticides, solvents, etc.), as well as at the place of work of a woman. A special form from the employer is desirable.

Discussing issues of alcohol abuse and smoking. If necessary, help in the rejection of bad habits.

Clarification of medical problems:

Diabetes - control optimization.

Hypertension - replacement of ACE inhibitors, angiotensin II receptor antagonists, thiazide diuretics with drugs that are not contraindicated in pregnancy.

Epilepsy - control optimization, folic acid - 1 g per day.

Deep vein thrombosis - replacement of coumadin with heparin.

Depression/anxiety - exclude benzodiazepines from drug therapy.

Avoid overheating (avoid hot baths, saunas, steam rooms).

Discuss problems of obesity and excessively low weight (if necessary).

Discuss possible nutritional deficiencies in vegetarians, milk intolerant women, calcium and iron deficiencies.

Warn about the need to avoid overdose:

Vitamin A - (limit - 3000 IU per day)

Vitamin D (limit - 400 IU per day)

Caffeine (limit 2 cups of coffee and 6 glasses of caffeinated drinks (coca-cola) per day)
__________________

When registering and further managing pregnancy in Russia, the following examination must be performed:
-dab on Gn and trich
-RW, f-50, HbSAg, HCV,
-an. blood vol.
-an. urine
-feces on i \ worm
- examination for toxoplasmosis, CMV
- sowing on ureaplasma and mycoplasma
- test for chlamydia
- consultations of specialists: therapist, ENT, dentist, ophthalmologist; the rest according to indications
There is no hiding from this examination, there is an order of the Ministry of Health No. 50, all of Russia is working on it.

Hi all! I still won’t leave the next conference for you, I’m just afraid, because. Failed 2 times. Now, too, not everything is going smoothly, but I'm still on another issue. The thing is, I have a deadline. on monthly and on US differs. If according to the monthly, according to the standard calculation (LPM on January 26), it should be 11 weeks and 4 days today, then according to the ultrasound it turned out 10 weeks 5 days. There is an ultrasound of April 14 (term 10 weeks 3 days). The doctor, when she saw him, said that it was too early for screening and you would come for an ultrasound on April 25, and for ...

Discussion

Here is the info about the first screening. About everything, including timing.

Pregnancy-associated plasma protein-A. In prenatal screening of the first trimester of pregnancy, a risk marker for Down syndrome and other fetal chromosomal abnormalities.

PAPP-A is a high molecular weight glycoprotein (m.v. about 800 kDa). During pregnancy, it is produced in large quantities by trophoblasts and enters the maternal circulation system, its concentration in the mother's blood serum increases with increasing gestational age. Based on their biochemical properties, PAPP-A is classified as a metalloprotease. It has the ability to cleave one of the proteins that bind the insulin-like growth factor. This causes an increase in the bioavailability of insulin-like growth factor, which is an important factor in fetal development during pregnancy. It is assumed that PAPP-A is also involved in the modulation of the maternal immune response during pregnancy. A similar protein is also present in low concentrations in the blood of men and non-pregnant women. The physiological role of PAPP-A continues to be explored.

A number of serious clinical studies indicate the diagnostic significance of PAPP-A as a screening marker for the risk of fetal chromosomal abnormalities in early pregnancy (in the first trimester), which is fundamentally important in the diagnosis of chromosomal abnormalities. The level of PAPP-A is significantly reduced if the fetus has trisomy 21 (Down syndrome) or trisomy 18 (Edwards syndrome). In addition, this test is also informative in assessing the threat of miscarriage and termination of pregnancy in the short term.

An isolated study of the level of PAPP-A as a marker of the risk of Down syndrome has diagnostic value, starting from 8-9 weeks of pregnancy. In combination with the determination of beta-hCG (human chorionic gonadotropin), the determination of PAPP-A is optimally carried out at a period of about 12 weeks of pregnancy (11 - 14 weeks). After 14 weeks of gestation, the diagnostic value of PAPP-A as a risk marker for Down syndrome is lost. It has been established that the combination of this test with the determination of the free beta subunit of hCG (or total beta-hCG), ultrasound data (nuchal thickness), assessment of age-related risk factors significantly increases the effectiveness of prenatal screening for Down syndrome in the first trimester of pregnancy, bringing it to 85 - 90% detection rate of Down syndrome with 5% false positive results. The study of PAPP-A as a biochemical marker of congenital and hereditary pathology in the fetus in combination with the determination of hCG at a period of 11-13 weeks of pregnancy is currently included in the scheme of screening examinations of pregnant women in first trimester.

The detection of deviations in the levels of biochemical markers in the mother's blood is not an unconditional confirmation of fetal pathology, but, in combination with the assessment of other risk factors, it is the basis for the use of more complex special methods for diagnosing fetal anomalies.

Indications for the purpose of the analysis:

Screening examination of pregnant women to assess the risk of fetal chromosomal abnormalities in the 1st and early 2nd trimesters of pregnancy (11 - 13 weeks);
Severe complications of pregnancy in history (in order to assess the threat of miscarriage and stop the development of pregnancy in the short term);
The woman's age is over 35;
The presence of two or more spontaneous abortions in the early stages of pregnancy;
Bacterial and viral (hepatitis, rubella, herpes, cytomegalovirus) infections transferred during the period preceding pregnancy;
The presence in the family of a child (or in history - the fetus of an interrupted pregnancy) with Down's disease, other chromosomal diseases, congenital malformations;
Hereditary diseases in close relatives;
Radiation exposure or other harmful effects on one of the spouses before conception.
Preparation for the study: not required.

Material for research: blood serum.

Method of determination: immunoanalysis.

Girls, hello everyone! I recently asked you for advice on how to support yourself in the early stages before a visit to the doctor. Finally got in yesterday. Outcome: 6 weeks. 2 days, continue treatment. HURRAH! Thank you for your advice. Now here's what I'm thinking. I am 36, I want to do everything right and give birth to a child without diabetes. The doctor says that non-invasive diagnostics is, of course, good and the only question here is money. But screenings still need to be done, because. while there is not enough accumulated in non-invasive diagnostics ...

Discussion

Good afternoon! I don’t really understand the doctor’s position, the fact is that screenings and a non-invasive test are fundamentally different. Screenings are probabilities, they do not make any diagnoses, since all results can indirectly indicate pathologies. Non-invasive screening is the isolation of the child's blood from the mother's blood and the study of the child's DNA from these cells. Accordingly, the result is more accurate. I write more, because they have an error in very small cases, but in general they are accurate. The most accurate methods are invasive. I would do a non-invasive screening right away.

02/07/2019 13:06:39, Svetlana__1982

Donov ultrasound, excellent doctor. For example, I saw my third large teeth in the gums on the second ultrasound, while I have ordinary ones, and my husband and older children have large ones - he didn’t know this!
About the analysis, now there is some kind of super-duper blood test in the PMC, they definitely did it a year ago.

Well, I just can’t resist talking about the meaning of life ... If you are not ready to accept what life gives you, keep in mind that it will still force you to accept something, which is very repulsive, and the degree of rejection, unfortunately, will be higher each time (

Girls, I would like to hear opinions, maybe there are among you who had 3 caesarean sections. We are thinking about another baby, well, we really want to. But I am 40 years old and already had 2 caesarean sections, the last 7 years ago. The gynecologist said that there are very big risks. What do you think?

Discussion

There were 4 cesareans. 4th 2 weeks before my 43 years old .. I brought everyone to the end (they were scheduled to get it a week before the deadline), but I’m large, and the children were standard, mb lucky in this .. The risks are big after 40 according to Down and it’s not easy for you it will most likely be due to health (in 30 years everything is different, much easier). Usually they scare everyone, and then there’s just nowhere to go and everything becomes normal .. You can also somehow see the solvency of the seam, why you are so afraid for it .. I know people and 6 times Caesar (mostly believers), somehow withstand all..

I had three cesarean sections, I still think about it, but the doctors say there is a risk, but after the third one everything was fine

12/19/2018 02:12:00 PM, Oksana Astrelin

Yesterday they called me at home and told me to come urgently to the clinic - the results of the first screening came. I’ll omit about the sleepless night, perhaps, because I want to rely on facts. The gynecologist did not answer the questions, said that this was not about her part and redirected. The numbers are: The risk of having Down syndrome is 1:325 Mom according to HCGB- 3.10 according to PAPP-A 2.1 It is written that the limits for Mom are from 0.5 to 2.0, but I get 3.1, is it really much higher than the norm? What is the upper bound when the threshold risk goes to...

Discussion

Most likely nothing to worry about. Your HCGB is indeed elevated, but with Down syndrome it is usually in combination - PAPP-A is reduced. And yours is even slightly higher than normal. The program considers you a threshold risk due to elevated HCGB, although there are many other reasons for its increase, not only chromosomal problems. And what do you have on the ultrasound? Collar space, nasal bone?

It was 1 to 300 everything is ok. girlfriend 1k 180 everything is ok. the second girlfriend has 1 to 80 and amnio - everything is ok! @@@ [email protected]@@[email protected]@@[email protected]@@@@@

Girls, who did it? My gynecologist said that they only do it if the blood test for Down came up bad. I visited a geneticist, so she silently, without telling me anything, wrote that she recommends a puncture. Next week I'm going to the doctor, the result of a blood test for Down should already come. So I'm sitting all in confusion ... Who did they do it to? Who knows what?

Discussion

I did it on April 15 at the perinatal center at the 27th maternity hospital near Sypchenko. The indications are poor screening and age (I am 40 years old).

05/04/2010 13:27:19, Makhryuta

Thanks for answers. My due date is 21-22 weeks. I will talk to the geneticist again, on the basis of which she recommends me. I have all the tests, ultrasounds are good, only age. I am already 37 years old. I think that, probably, only by age and directs .... (((

Women who are overweight and obese are more likely to experience pregnancy complications and have an increased chance of having a baby with birth defects, warn the authors of a report released by the U.S. Teratology Society Public Affairs Committee. According to the report, overweight women are more likely to suffer from infertility and pregnancy complications such as hypertension, cardiovascular disease and diabetes. Physicians are more likely to...

Pregnant women suffering from periodontitis are more often prone to late toxicosis - preeclampsia, informs the Journal of Periodontology. Studies have shown that 64% of women suffering from periodontal disease were diagnosed with preeclampsia, and 36% of the study participants had an uneventful pregnancy. Preeclamptic mothers-to-be have been noted to have more severe gum disease. As part of the study, women were tested for Eikenella bacteria ...

Please advise. I went to the first ultrasound, they determined the pregnancy of 4-6 weeks. The doctor who did the ultrasound said there was a risk of miscarriage, but did not explain why. The gynecologist prescribed duphaston, buscopan suppositories and vitamin E. The annotation says that buscopan should be taken with caution during pregnancy, the rest, in principle, too. Can, in fact, I have a risk of miscarriage (I'm 26 years old, nothing hurts, I don't bleed) or are doctors playing it safe? Isn't it bad...

Discussion

good luck to you! @@@ [email protected]

Girls! I went again to the same doctor, as it was necessary to take all the tests that were ready today. Once again I asked her about the threat, she said that there was no detachment and tone, but the shape of the fetus, which should be round, was oblong. The diagnosis sounds: pathology of fetal development. Once again she said that she needed to take medicine. The analyzes are all right. Again I don't know what to do. Perhaps I am wasting my time looking for another doctor.

02/03/2012 08:50:58, EvaK

Girls, good evening! I will gladly join you, if you accept of course). I am 40 years old, B 14 weeks now, twins. I myself am still in shock, we don’t have such a husband in our family. I have an 18 year old son from my first marriage. I had an ultrasound at 12 weeks for screening, everything was normal. A blood test is now ready and a blood test. Down's syndrome (only for biochemistry) high risk 1:94, risk limit 1:250. The rest is low risk, they gave a referral to genetics. I read information that with twins, blood screening does not ...

Discussion

Do an amnio. You will know for sure.

I was done at 16 weeks, SVS.

08.11.2013 23:45:05, masha__usa

I was in your situation 1.5 years ago. I had an even higher risk than you, 1:53, only for Edwards syndrome. And I was only 33 years old. I did a biopsy of the placenta at 14 weeks on the recommendation of a geneticist. Suspicions were not confirmed, fortunately. But, quite possibly, because of this invasive procedure, my son is not completely healthy in neurology. If I were you with twins, I wouldn't risk it and hope for the best.

What pathologies can occur in a child as a result of stress during pregnancy (for example, a mother experienced a break with her beloved, or problems at work, or just had a fight with her parents forever!) ... How dangerous is this for the unborn child? (I asked the same question in "Pregnancy and childbirth" - but here I hope to hear the opinion of a specialist or links to medical articles)

Discussion

I am an expert, so my opinion is amateurish, but I have my own experience. The first pregnancy was very nervous, I had to hide the pregnancy, my husband could not get a divorce from his first wife and my father kicked me out of the house. The child was born normal, as I later realized, not even very noisy. The second pregnancy proceeded in absolute peace of mind, there was not even any unrest at work, since I was sitting at home. And the baby was born restless, with-hands-not descending.

The child has the type of nervous system that he inherits from his parents. After all, it often happens that the same parents have completely different children: one is completely calm, the other is hyperactive with distracted attention. That is, what is pledged is pledged. So it doesn't depend on stress. IMHO If, during pregnancy, a woman endures prolonged stressful situations, everything depends, in my opinion, firstly, on the type of nervous system of the woman herself, secondly, on her state of health at the current moment, and, thirdly, on the attitude of the woman herself women to what happened. And since any stress can cause unpredictable consequences for human health (from a headache to a heart attack), it is precisely the peculiarities of the course of these consequences in a pregnant woman that will affect the fetus. The consequences can be different and are known, probably, to everyone. These are mainly vegetative-vascular disorders: increased pressure, panic attacks, palpitations, headaches, lack of appetite, insomnia, depression, etc. This, in turn, can cause (as in a chain reaction) complications during pregnancy and even the threat of miscarriage. It seems to me that mother nature tried to protect the nervous system of a woman from such things during pregnancy. If the pregnancy is desired and the child is long-awaited, then this is such a positive emotion for a woman that she endures many stressful situations much easier. So, I think there will be no pronounced pathologies in a child born to a mother whose pregnancy proceeded in stressful situations, but without complications and consequences for her health. If, as a result of these stresses, the mother's health deteriorated and, as a result, complications arose during pregnancy, then the answer is obvious - there will be deviations, but not necessarily in the development of the child's nervous system. Here, everything will depend on the stage of pregnancy at which these stressful situations that led to the illness of the mother were.

My sister-in-law is offered to undergo a study: a puncture of the amniotic fluid. Motivated by the fact that her age is 36 years. Childbirth 2nd. I would like to hear the pros and cons. Who faced it? She needs to decide whether or not to puncture.

Discussion

Thanks to all who answered! The question is really very important. And forgive me for opening up the wounds and making me nervous again. Health to you and your children!

I did 2 times (in 2 and 3 pregnancies).
The first pregnancy was 10 years ago, there were no screenings at that time. The girl is healthy and smart. They really wanted a second child, but could not zaB., I was stimulated, zaB. in 2008 The pregnancy was very difficult: on hormones, low placentation, tone, bled once, lay on conservation.
But according to the ultrasound, at first everything was fine with the child: at 12 weeks - the collar zone (one of the SD markers) was normal, at 16 weeks - the ultrasound was normal. 1st screening was elevated, 2nd screening was normal.
At 18 weeks, I decided to have an amniocentesis, but my husband and parents were against it - everyone was afraid of a miscarriage. After 2 weeks, the result came - a child with diabetes. They did an ultrasound (it was already 20 weeks old) - there were changes in the heart, enlarged pelvises, the child began to lag behind in terms. They said it would only get worse. Ultrasounds were altered in different places (without voicing the diagnosis obtained after amniocentesis). The geneticists said it was a spontaneous mutation. I was then only 32 years old.
Now I'm pregnant again! Zab. alone, without hormones.
My husband and I went for a consultation to the Institute of Genetics on Kashirskoye Highway. They said that the risk of screenings would immediately be increased, tk. there was such a situation in the past. On ultrasound, chromosomal pathologies may not be seen. Knowing myself that I will wear out all the nerves for myself and the child, I decided to have a chorion biopsy at 10 weeks. I was madly afraid, because again afraid of losing the child. Everything went well - the child is healthy. Now I sleep peacefully at night, I go and enjoy my pregnancy, I have not taken any screenings.
If your sister-in-law doesn't panic if she gets a bad screening result (or won't give them at all) if she's going to have a baby anyway, then you can skip the amniocentesis. It depends on her inner mood, on her attitude to all this.
Moreover, amniocentesis (collection of amniotic fluid is considered) is the safest, and chorion biopsy (collection of chorion particles) is the most dangerous, because. little time.
I did no-shpy injections 2 days before and after the procedure and inserted papaverine suppositories. 1 case in the Center for Psychological Prevention and Rehabilitation in Sevastopolsky (doctor in charge of the department - Gnetetskaya), 2 times in the perinatal center at the 27th maternity hospital (doctor in charge of the department Yudina).
Good luck! Health to your sister-in-law and baby! Everything will be fine!!!

03/25/2010 19:41:48, did

Has anyone taken atenolol? I have a brutal arrhythmia with extrasystoles .. It seems to be giving birth in special. maternity hospital is necessary: ​​(((((. And they write about atenolol that it is necessary to take it with caution .. and if the benefit for me is higher than the risk for the baby. Now I'm afraid ...

Received today the result of the second screening. The first one was perfect, I relaxed and drove for a week after the result. And then they doused it with ice water. High risk of Down syndrome 1:30. The first screening is 1::2200, although I am 36 years old, it should be 1:290 by age. In general, I’m still in shock, my doctor for Oparin is on vacation (only for an appointment on August 8), until that time you can move your mind. I looked at the markers, the problem is in hcg. I'm in the morning, maybe, of course, it also affected ... I'm afraid to do amniocentesis ...

Girls, hello. Here was today at the doctor in ZhK. The result came from the second screening (the first screening was good), a high risk for Down syndrome, the calculated risk is 1: 160, I am now 20 weeks old, I called at 17 p.m. (I was given a referral to a genetics consultation), they said that the appointment was only for On July 1, and at that time, the geneticist no longer consults. Who should I contact, no one will advise a competent specialist in order to finally understand everything? I know that I will...

Discussion

Many doctors say, including Voevodin, that the first screening is most indicative of Down syndrome, and not the second.

I had a similar situation, the first screening was good, the second was bad for Down syndrome, everything darkened in my eyes from such news - shock, tears. I’ll give up the child. They wanted to withdraw a small amount of water, but I wrote a refusal and didn’t even visit genetics. I went for an ultrasound to a specialist in the Vojvodin syndrome, at that time, somewhere in October, he worked at the Planet of Health, showed me everything, explained and said that I shouldn’t take a steam bath and don’t take water because this procedure carries a high risk of miscarriage. And my gynecologist said that such screenings have become more frequent, but absolutely everyone gives birth to healthy babies. The laboratory mows down, and the result often depends on many factors - excess weight, even from the products that they ate the day before. I can perfectly understand you anyway, after such news, I could not fully enjoy the expectation of a miracle, even when they didn’t bring me a child on the first day, I thought that the doctors th they hide about it. But my baby is just resting after a difficult birth. Go to Voevodin.

Today I visited a geneticist at the TsPSiR in Sevastopol. The doctor suggested a study of amniotic fluid, I agreed. I was surprised when I found out that the study is carried out even without local anesthesia. I ask those who have passed the same research to respond. Please tell me how painful it is and how quickly you recovered.

Discussion

Mytil, this study is not very painful, it looks like an injection or blood sampling from a vein. Anesthesia is not required. But rest is needed for a few days. Immediately after the procedure, they are left in the ward for 2-3 hours, and then you can go home, lie down, and relax.
I have great respect for the specialists of the Center for Social and Social Development, and I thank them for their help. However, I cannot but be surprised that it is in this institution that the indications for cordocentesis (analysis of cord blood, results in 5-7 days) and amniocentesis (analysis of amniotic fluid, results in 2-3 weeks) due to different features in the results of ultrasound and blood tests are prescribed to almost every pregnant woman. I have an assumption that the geneticists working there write dissertations, and this requires research statistics.
Do an analysis if you are restless - half the pregnancy to live in anxiety is an even greater risk for the baby. I wish you everything goes well.

12.10.2006 10:41:23, We went through this

As for the topic...
She herself went through this 3 times, and if it was still required, she still went through it.
The first time, too, there were deviations on the triple test. After amniocentesis, it was necessary to do cordocentesis (the same puncture, only blood from the umbilical cord is taken for analysis). They found that the placenta is slightly mutated, hence the discrepancies in the analyzes. But after the analysis, there is complete confidence that everything is in order. "The child has a genetic passport that there are no gene deviations 99.9%" (c)
Third time in my second pregnancy. The analyzes are also slightly outside the norm. And I went through it again.
Regarding the procedure itself, it is almost painless, they ask me to lie down for 2 hours after that, they do a control ultrasound and, if everything is in order, they send me home. On this day, they give sick leave, and the next. day to work is possible. The first 2 times the procedure took 20 minutes (in 2002), the third time - 5 minutes (probably already filled with a hand).
IMHO I wouldn't be able to do otherwise. It is my choice.

11.10.2006 06:54:16, Elena__

Received today analysis. "high risk of down syndrome" ......... 1 to 197 ......... The doctor said: "redo the screening, suddenly the error of the laboratory" . I did the screening in Art-med, I have a doctor in another clinic, and I will redo it in it. I'll go on Monday. Keep your fists..........

Discussion

With my second son, I had almost the same screening result of 1:175. But I found out about it by the time the second screening came up. I didn’t do the second one, I went for an ultrasound to Malmberg (I think it’s spelled that way) - she is an excellent specialist in developmental anomalies - the ultrasound showed that everything is fine. I also went to a geneticist - he asked everything about hereditary diseases, bad habits and said that this was most likely a false positive. result. Also, in the initial stages, I took duphaston, the doctor said that he could have an effect. She explained that they take the mother's blood and try to determine what is happening with the child. This is a VERY unreliable analysis, which can be influenced by a bunch of factors. In short, I didn’t worry anymore, everything is fine with the child.

My risk was much higher. She refused amnio, but when the second screening was done, the result was even worse. Did for fidelity in two different places. I had a cordocentesis at 22 weeks. 3 minutes, not painful and not scary. They did it in RD 17, head of the department of genetics. I got there in the direction from the LCD. In the end, everything is fine. But my nerves to wait until the birth of a child would not be enough. And for sure, it would be worse for the child.

The relevance of this issue has become more and more obvious lately :) Girls, do not be lazy, connect! Pregnancy FAQ Managers, please include the collected statistics in the FAQ. So. Please look into your documents and see all 1st trimester screening figures. I explain: this is an ultrasound scan at 10-13 obstetric weeks (from menstruation) and blood for PAPP-A and free betta hCG. 1) Pregnancy period 2) TVP (collar space) by ultrasound 3) The result of PAPP-A in units (and norms in brackets) 4) ...

Discussion

Hello. Help dispel my worries about the results of 1 screening.
I am 37 years old, we are on the 5th, there was no birth. Previously, there were 2 deputy pregnancies, ectopic and after an accident (2009) long treatment and rehabilitation (this is all that is indicated in the anamnesis). According to genetics, a predisposition to Thrombophilia, but none of the relatives was noticed. I give Enoxaparin 4000 injections 1 injection per day. Dufaston 1 tab. 3 times a day.
The results of 1 screening came yesterday. Although the doctor warned on the ultrasound that the blood would definitely not be ice with age and taking Duphaston, but the main thing is that according to the ultrasound, everything is fine with us.
1) The term was set at 12 weeks 3 days (everything is the same day to day) both according to ultrasound and DPM.
2) TVP -2.1 mm, CTE -61 mm, BPR - 19 mm, OG - 73 mm, coolant -58 mm, Chorion - low on the back wall, Nasal bone - is determined, no fetal pathologies were detected by ultrasound, the length of the church canal was at 10-11 weeks 35-36mm, at the time of ultrasound 39mm.
3) PAPP-A 3.340 IU/l
4) PAPP-A 1.494 MoM
5) betta hCG 22.00 IU/l
6) betta hCG 0.584 MoM
Uterine arteries PI: 1.490 or 0.937 MoM
7) Trisomy 21 Baseline risk 1:145, Individual adjusted risk 1:2906
Trisomy 18 Baseline risk 1:350, Individual adjusted risk 1:7000
Trisomy 13 Baseline risk 1:1099, Individually adjusted risk Pre-eclampsia before 34 weeks 1:1288
Preeclampsia up to 37 weeks 1:244
Growth retardation up to 37 weeks. 1:720
Spontaneous delivery up to 34 weeks. 1:1461
8) At the time of the research on 08/08/18 (12 weeks and 3 days):
- Defects and anomalies of the fetus - NOT DETECTED
-Risk of fetal chromosomal abnormalities - INCREASED
- Risk of preeclapsia and fetal growth retardation -LOW

Pregnancy 2a, 29 years old, first with a healthy boy. Real 13 weeks 3 days, TVP 1.8. According to ultrasound, the nasal bone is 1.6. But the ultrasound was redone the next day and the nasal bone was 2.2 mm, KTP 64MM. And the blood data and risks were calculated for the 1st ultrasound: B-hCG 44.01 IU / l / 1.336 MoM (norms not indicated), PAPP-a PAPP-2.719 IU/l/0.597 MoM...equipment BRAHMS kryptor. Trisomy 21 baseline risk 1:724, individual 1:42, others do not exceed

13.02.2018 19:21:01, [email protected]

Health experts have long been saying that women should take at least a two-year break between births, but a new study suggests that this is not enough. Several recent studies show that babies born three to five years after previous births are less likely to be born prematurely or underweight than those born after a shorter interval. The increase in the break between children is also beneficial for mothers ...

At present, the optimal mode of delivery for infected women has not been fully determined. To make a decision, the doctor needs to know the results of a comprehensive virological study. Natural childbirth includes a whole range of measures aimed at adequate analgesia, prevention of fetal hypoxia and early rupture of amniotic fluid, and reduction of trauma to the birth canal in the mother and skin of the baby. Only when all preventive measures are observed ...

Discussion

Absolutely agree. Unfortunately, at the moment there is no consensus on the safest management of childbirth with hepatitis C. According to statistics, the likelihood of a child being infected with hepatitis is slightly lower with a planned caesarean section than with natural childbirth. However, none of these methods can guarantee the safety of the child in terms of infection with hepatitis. Therefore, the choice of method of delivery is based more on the obstetric history than on knowledge of the presence of this infection.

Any person who is preparing to become a parent wants his child to be healthy, so that the pregnancy goes as smoothly and easily as possible. And possible threats come not only from external negative factors, but also from internal ones, and one of them is genetics. All biological characteristics that are inherited are contained in the 46 chromosomes that make up the genetic set of each person. These chromosomes contain encrypted information about many, many generations of the genus...

The most common complications associated with twin/twin/triple pregnancy are: Premature birth. Low birth weight. Retardation of intrauterine development of the fetus. Preeclampsia. Gestational diabetes. Placental abruption. C-section. premature birth. Births that occur before the 37th week of pregnancy are considered premature. The duration of a multiple pregnancy decreases with each additional child. On average, a pregnancy with one baby lasts 39 weeks ...

Recently, the number of women who decide to give birth to their first child after 35 and even after 40 years is growing. And if earlier women who gave birth after 28 years were already considered “old-timers”, today this does not surprise anyone. In the modern world, many women postpone the birth of children indefinitely because they first want to achieve career success, improve their financial situation, stabilize their personal lives, because now the age of marriage has also increased. Due to the fact that under...

Discussion

Hello Olga!
I really liked your article about late children. So detailed and very well built logically. And most importantly - so well conveying my own thoughts. I also gave birth to a child at almost 40 and do not regret it at all. I think if I had given birth earlier, there would have been more problems and much less satisfaction. I hope you raise this topic in your blog more than once, and we will read and comment :-) Therefore, I subscribe to your RSS feed. Thanks again!

09/23/2012 12:46:53 PM, Olga Merleva

Over the past decades, life has made significant changes in the relationship between the doctor and the patient. Currently phrases like; “The doctor forbade me to give birth!” - cause a smile and seem to be borrowed from a women's magazine of the middle of the last century. Now doctors do not “prohibit” anything, and even if they did, the patients, it seems, would not be in a hurry to follow such directives. A woman has the right to independently decide the issue of motherhood - this is evidenced by the current legislation and common sense. Meanwhile, it should be noted that over these decades, the health indicators of the female population of Russia have not improved significantly. In addition, the proportion of older women in childbirth is increasing year by year - a modern woman often seeks to first strengthen her position in society and only then have children. It is no secret that over the years we do not get younger, and accumulate a number of chronic diseases that can affect the course of pregnancy and childbirth.

Igor Bykov
Obstetrician-gynecologist

Modern science knows several thousand diseases. Here we will talk about the diseases that are most typical for women of childbearing age, and their impact on the course of pregnancy.

Hypertension 1 is one of the most common chronic diseases among young women. Manifested by vascular spasm and a persistent increase in blood pressure above 140/90 mm Hg. In the I trimester, under the influence of the natural factors of pregnancy, the pressure usually decreases somewhat, which creates the appearance of relative well-being. In the second half of pregnancy, the pressure increases significantly, pregnancy, as a rule, is complicated by preeclampsia (this complication is manifested by an increase in blood pressure, the appearance of edema, protein in the urine) and insufficient supply of oxygen and nutrients to the fetus. In pregnant women and women in labor with hypertension, complications such as premature detachment of a normally located placenta, postpartum hemorrhage, and cerebrovascular accident are not uncommon. That is why patients with severe hypertension (a significant increase in blood pressure) are sometimes recommended to terminate the pregnancy at any time.

If the risk is low, the district gynecologist observes the pregnancy together with the therapist. Treatment of hypertension during pregnancy is mandatory and differs little from the treatment of hypertension outside of pregnancy. Delivery, in the absence of other indications for surgery, is performed through the natural birth canal.

Arterial hypotension 2 quite common in young women and is manifested by a persistent decrease in blood pressure to 100/60 mm Hg. and below. It is easy to guess that problems with hypotension begin in the first trimester, when blood pressure already tends to decrease.

Complications of arterial hypotension are the same as in hypertension. In addition, during pregnancy there is often a tendency to overbearing, and childbirth is almost always complicated by the weakness of the birth forces.

Treatment of hypotension during pregnancy consists in normalizing the regime of work and rest, taking fortifying agents and vitamins. Hyperbaric oxygen therapy is also used (a method of saturating the body with oxygen under elevated barometric pressure). Delivery is carried out through the natural birth canal. Sometimes prenatal hospitalization is required before childbirth in order to prepare the cervix for childbirth and prevent overgestation.

Varicose disease 3(violation of the outflow of venous blood as a result of a deterioration in the functioning of the valvular apparatus of the veins, expansion of the veins) affects mainly the lower extremities and the vulva. Most often, varicose veins are first detected or first appear during pregnancy. The essence of the disease consists in changes in the wall and valvular apparatus of peripheral veins.

Uncomplicated varicose veins are manifested by dilatation of the veins (which is perceived by pregnant women as a cosmetic defect) and pain in the lower extremities. Complicated varicose disease suggests the presence of other diseases, the cause of which is a violation of the venous outflow from the lower extremities. These are thrombophlebitis, acute thrombosis, eczema, erysipelas (an infectious disease of the skin caused by pathogenic microbes - streptococci). Fortunately, complicated varicose veins are rare in young women.

Childbirth in patients with varicose veins is often complicated by premature detachment of the placenta, postpartum hemorrhage. Childbirth is carried out through the natural birth canal, if pronounced varicose veins of the external genital organs do not prevent this. During pregnancy and in the postpartum period, physiotherapy exercises and elastic compression of the lower extremities are necessary - the use of special tights, stockings or bandages that have a compressive (compressive) effect on the venous wall, which reduces the lumen of the veins, helps the venous valves work.

Heart defects are diverse, so the course of pregnancy and its prognosis in such cases are very individual. A number of severe defects, in which the heart cannot cope with its functions, is an absolute contraindication to carrying a pregnancy.

The gynecologist observes the rest of the pregnant women with heart defects in close contact with the therapist. Even if the pregnant woman feels good, she is sent for planned hospitalization at least three times during pregnancy: at terms of 8-12, 28-32 weeks and 2-3 weeks before delivery. In the absence of heart failure, delivery is through the natural birth canal. To exclude attempts, the imposition of obstetric forceps is sometimes used. Particular attention is paid to anesthesia in order to prevent an increase in the load on the heart under stress. A caesarean section is not advantageous in women with heart defects, since the operation itself is no less stressful on the cardiovascular system than natural childbirth.

Bronchial asthma- an allergic disease. Pregnancy sometimes alleviates the course of asthma, sometimes it aggravates it significantly.

Bronchial asthma during pregnancy requires the usual treatment for this disease with bronchodilator drugs, used mainly in the form of inhalations. Asthma attacks are not as dangerous for the fetus as it is commonly believed, since the fetus is much more resistant to hypoxia (oxygen starvation) than the mother's body. Conducting childbirth on the background of bronchial asthma does not require any significant adjustments.

Pyelonephritis 4 fairly common among women of childbearing age. This is an inflammatory disease of a microbial nature that affects the tissue of the kidney and the walls of the pelvicalyceal apparatus - the system through which urine flows from the kidneys. During pregnancy, pyelonephritis is often first detected, and long-term chronic pyelonephritis is often exacerbated due to the fact that pregnancy represents an increased functional load for the kidneys. In addition, the physiological bends of the ureters are aggravated, which creates favorable conditions for the habitation of pathogens in them. The right kidney is affected somewhat more often than the left or both.

A contraindication to pregnancy is a combination of pyelonephritis with hypertension, renal failure, and pyelonephritis of a single kidney.

Pyelonephritis is manifested by lower back pain, fever, detection of bacteria and leukocytes in the urine. The concept of "asymptomatic bacteruria" is distinguished - a condition in which there are no signs of an inflammatory process in the kidneys, but pathogenic bacteria are found in the urine, which suggests that they inhabit the renal pelvis and urinary tract in abundance. Like any inflammatory process, pyelonephritis is a risk factor for intrauterine infection of the fetus and other elements of the fetal egg (chorioamnionitis, placentitis - inflammation of the membranes, placenta). In addition, pregnancy in patients with pyelonephritis is much more often complicated by preeclampsia with all its attendant troubles.

Pyelonephritis and asymptomatic bacteruria are subject to mandatory treatment with antibiotics and agents that improve urine excretion. Childbirth in this case, as a rule, proceeds without features. Children born to mothers with pyelonephritis are more likely to be prone to purulent-septic diseases.

diabetes mellitus 5 during pregnancy poses a serious threat to the health of the mother and fetus. The obstetric classification of diabetes distinguishes between pregestational (existing before pregnancy) diabetes and gestational diabetes, or "diabetes in pregnancy" (impaired glucose tolerance, manifested in connection with pregnancy).

Diabetes mellitus has a number of categorical contraindications to pregnancy. This is diabetes complicated by retinopathy (damage to the vessels of the eyes) and diabetic nephropathy (damage to the vessels of the kidneys); diabetes resistant to insulin treatment; a combination of diabetes and Rhesus conflict; the birth of children with congenital defects in the past; as well as diabetes mellitus in both spouses (since in this case there is a high probability of having children with diabetes).

The first half of pregnancy in diabetic patients often proceeds without complications. In the second half, pregnancy is often complicated by polyhydramnios, preeclampsia, pyelonephritis.

1 You can read about folk remedies used for hypertension during pregnancy in the magazine "9 months" No. 7/2005.
2 You can read about folk remedies used for hypotension during pregnancy in the magazine "9 months" No. 6/2005.
3 Read more about varicose veins of the lower extremities in the magazine "9 months" No. 7/2005.
4 You can read more about pyelonephritis during pregnancy in the Pregnancy magazine No. 6/2005.

RUSSIAN ACADEMY OF MEDICAL SCIENCES

RESEARCH INSTITUTE OF OBSTETRICS AND GYNECOLOGY them. D. O. OTTA

V. V. Abramchekko, A. G. Kiselev, O. O. Orlova, D. N. Abdullaev

MANAGEMENT OF HIGH RISK PREGNANCY AND BIRTH

SAINT PETERSBURG

INTRODUCTION

Abramchenko V. V., Kiselev A. G., Orlova O. O., Abdullaev D. N. Management of high-risk pregnancy and childbirth.- St. Petersburg, 1995

Based on literature data and our own experience, the issues of identifying and managing high-risk pregnant women and women in childbirth are highlighted. Particular attention is paid to the treatment of women with complications of pregnancy and childbirth. In particular, the issues of managing pregnant women with breech presentation of the fetus, narrow pelvis, diabetes, and diabetes are highlighted. The second part of the monograph is devoted to a number of complications of pregnancy and childbirth: the regulation of labor activity, the prevention and treatment of mecoia aspiration syndrome, modern methods of treating fetal hypoxia

The book is intended for obstetrician-gynecologists, neonatologists and anesthesiologists working in obstetric institutions.

V. V. Abramchenko, A. G. Kiselev, O. O. Orlova, D. N. Abdullaev.

In Russia, the main goal in the field of maternal and child health" is to develop conditions for "preserving the health and working capacity of women, addressing issues of rational tactics - managing pregnancy 1 , childbirth, the postpartum and neonatal period, identifying ways to reduce maternal, perinatal and child morbidity and mortality . At the same time, the creation of optimal conditions for women's health and the development of pregnancy is the basis of "Prevention of perinatal pathology. O. G. Frolova et al. (1994) consider the reduction of reproductive losses to be one of the main directions in the protection of motherhood and childhood. The authors propose to consider reproductive losses as the end result of the influence of social, medical and biological factors "and the health of pregnant women and newborns. The authors refer to reproductive losses as the loss of embryos and fetuses throughout the entire gestation period. On average, 32.3% of all pregnancies in the Russian Federation end in childbirth.

According to statistics, high-risk pregnancies in the general population are approximately 10%, and in specialized hospitals or perinatal centers they can reach 90% (Yu. I. Barashnev, 1991 and others). Materials from WHO (1988) show that in Europe we are still far from defining what a rational birth technique should be.

In the work of the World Health Organization (WHO, Geneva, 1988, 1992), "family protection programs, in particular, maternal and child health, are also assigned a priority task. It is emphasized that deaths in the perinatal period are responsible for most of the stable and catastrophic high rates equal to infant mortality It has been shown that * perinatal mortality is closely associated with poor health and nutrition of the mother, complications of pregnancy and childbirth.

V. V. Chernaya, R. M. Muratova, V. N. Prilepskaya et al. (1991) recommend, depending on complaints, general somatic and reproductive history, objective examination data, 3 health groups should be distinguished among those examined:

- Healthy- in the anamnesis there are no violations in the formation and subsequent course of menstrual function, there are no pinecolic diseases, complaints; with an objective examination (laboratory and clinical), there are no changes in the structure and function of the organs of the reproductive system.

- Practically healthy- in the anamnesis there are indications of gynecological diseases, functional abnormalities

or abortions; there are no complaints at the time of the examination, or an objective examination may be anatomical changes that do not cause dysfunction of the reproductive system and do not reduce the working capacity of women.

__ sick- there may be (or be absent) indications of

gynecological diseases in history. Complaints at the time of the examination may or may not be present. An objective examination revealed the presence of a gynecological disease. On the. for the purpose of monitoring the state of health and the effectiveness of the medical and recreational activities carried out *, a “Control card of a dispensary patient (account file No. 30)” is entered for each patient.

Assessment of the health status of pregnant women should be carried out as follows:

The health of a pregnant woman can be considered as a state of optimal physiological, mental and social functioning, in which the race system! maternal organism ensure the usefulness of the health and development of the fetus.

The healthy group includes pregnant women who do not have somatic and gynecological diseases, who carry the pregnancy to the term of physiological childbirth. These pregnant women do not have risk factors for perinatal pathology.

To the group practically healthy pregnant women include women who do not have somatic and gynecological diseases, who carry their pregnancy to the term of normal delivery. The total assessment of the identified risk factors for perinatal pathology corresponds to a low degree of risk throughout pregnancy.

The rest of the pregnant women belong to the group sick, Assessment of the health status of the contingent of women who gave birth

should be carried out depending on the state of health at the time of pregnancy, childbirth and the postpartum period, with particular attention to the restoration of reproductive function.

The group of observation for puerperas is established at her first visit to the antenatal clinic.

Group I - includes healthy individuals with a physiological course of pregnancy, childbirth and the postpartum period, with sufficient lactation.

Group II includes practically healthy individuals with a physiological or complicated course of pregnancy, childbirth and the postpartum period, who have risk factors for the occurrence or worsening of extra genital and gynecological diseases; complaints" at the time of the examination are absent, with an objective examination there may be anatomical changes

niya, ve causing violations of reproductive function and the general state of health.

Group III includes patients with a physiological or complicated course of pregnancy, childbirth and the postpartum period, whose objective examination revealed the presence of obstetric pathology, gynecological diseases, worsening of the course of extragenital diseases.

The allocation of these groups is determined by the different nature of medical events.

Dispensary observation of the contingent of women who gave birth is carried out within a year after childbirth. In the future, regardless of the health group, “observation is carried out three times by actively calling those who have given birth to the antenatal clinic (by the 3rd, 6th and 12th months after birth). Three months after childbirth, a bimanual examination and examination of the cervix with the help of mirrors with the use of the Schiller test screening test (if possible, colposco-p "ii), bacteriological and pytological studies are performed. At this stage, health measures and individual selection of contraceptive methods are necessary.

At the 6th month after delivery, in the absence of contraindications, intrauterine contraception should be recommended. An active call for women to a consultation is carried out in order to control lactation, menstrual function and prevent unwanted pregnancy, social legal assistance. The third visit is advisable for the formation of an epicrisis on the final rehabilitation of women by the year after childbirth, the issuance of recommendations on contraception, planning subsequent pregnancy and women's behavior in order to prevent existing complications.

At the same time, it is essential to emphasize that the analysis of domestic and foreign literature shows that the level of perinatal morbidity and mortality is especially high in a certain group of pregnant women, united in the so-called. chew high-risk group. The allocation of such a group of pregnant women and women in labor allows organizing a differentiated system for providing obstetric and pediatric care to this contingent of women and<их новорожденным детям. В этой связи особое значение приобретает совершенствование организации акушерско-гинекологической помощи в сельской местности.

So far, the urgency of the problem of maternal mortality has not decreased. The level of maternal mortality in the Russian Federation is high, exceeding the corresponding indicator of developed economic countries by 6-10 times, and does not tend to decrease (Sharapova E.I., 1992; Perfilieva G.N., 1994). The analysis shows that the high level of maternal mortality is mainly due to abortion and such

obstetric complications, such as bleeding, preeclampsia and purulent-septic complications.

Great importance is attached to the relationship and interaction of an obstetrician-gynecologist and a paramedical worker in the prevention of a number of complications of pregnancy, childbirth and perinatal morbidity and mortality.

From rare diseases not related to pregnancy in the Russian Federation, 95- 110 women, accounting for 14-16% of all maternal deaths 1 . A significant influence of extratenital pathology on the formation of the most dangerous obstetric complications was also established. Thus, in women who died from obstetric bleeding, extragenital pathology was determined in 58% of cases, from gestosis - in 62%, from sepsis - in 68%. While in the population of pregnant women, extrahegoital diseases occur in 25-30% (Serov V.N., 1990).

The proposed monograph will acquaint the reader with the modern tactics of managing pregnancy and childbirth in high-risk groups.

Chapter I. High risk pregnant women

"Researchers from many countries are engaged in determining the factors and high-risk groups of pregnant women. At the same time, most authors, based on clinical data, identified risk factors, and then developed a system for their assessment. In the Russian Federation, the most thorough studies on the identification of risk factors belong to L. S. Persianinov and et al. (1976) The authors, based on a study of literature data, as well as a multifaceted development of birth histories in the study of the causes of perinatal mortality, identified individual risk factors.They included only those factors whose presence led to a higher level of perinatal mortality compared to L. S. Persianinov et al (1976) divided all identified risk factors into prenatal (A)

and intranatal (B).

Prenatal factors were divided into 5 subgroups: 1) socio-biological factors; 2) obstetric and gynecological history data; 3) the presence of extragenital pathology; 4) complications of this pregnancy; 5) assessment of the condition of the fetus. The total number of prenatal factors was 52.

Intranatal factors were divided into 3 subgroups: 1) maternal risk factors, 2) placenta, and 3) fetus. This group contains 20 factors. Thus, a total of 72 risk factors were identified (see Table No. 1). A number of authors

lie from 40 to 126 factors. Further, the authors point out that the analysis of literature data, evaluation of the work of antenatal clinics and maternity hospitals convinced that for obstetrics and gynecology practice at present, the scoring system for assessing risk factors should be considered the most acceptable. It makes it possible to evaluate not only the probability of an unfavorable outcome of childbirth in the presence of each specific factor, but also to obtain a total expression for the probability of the influence of a particular factor. The assessment scale of risk factors (in points) was developed by the authors based on the analysis of 2511 births that ended in fetal death in the perineum.

Table 1RISK FACTORS DURING PREGNANCY AND DELIVERY

anka > allah

Evka Zallah

A. ANTENATAL PERIOD

1. Socio-biological

III. Extragenital concerns

1. Age of the mother (years);

mother's left

1. History of infections

2. Cardiovascular diseases

heart defects

without violation

2. Father's age (years):

blood circulation

heart defects

in violation

3. Occupational harm

blood circulation

hypertonic disease

I-II-III stages

arterial hypotension

4. Bad habits: in the mother:

3. Kidney disease: before pregnancy

smoking 1 pack of cigarettes

exacerbation of the disease

during pregnancy

alcohol abuse-

4. Eidocrinopathies:

lrediabetes

alcohol abuse-

diabetes in family

thyroid disease

5. Marital status:

lonely

adrenal disease

6. Education:

5. Anemia:

initial

Not less than 9-10-11 g%

6. Coagulopathy

7. Emotional loads

7. Myopia and other eye diseases

Continuation

8. Height-weight indicators of the mother:

height 150 cm or less 1

weight is 25% higher than normal 2 II. Obstetric-gynecological history

I. Parity:

2. Abortions before the first birth:

3 4 3. Abortions before repeated childbirth:

4. Premature birth:

5. Stillbirth:

6. Death in the neonatal period:

7. Developmental anomalies in children 3

8. Neurological disorders 2

9. Weight of children less than 3500 2 and more than 4000 g. 1

10. Complicated course

previous rads 1

I1. Infertility more than 2 - 5

12. Scar on the uterus after operations 4

13. Maggoi and ovarian tumors 1 - 4

14. Isshiko-vdrvikalnaya insufficiency 2

15. Maggie Malformations 3

3 4

8. Chronic specific infections (tuberculosis, brucellosis, syphilis, current soplasmosis, etc. ______ 2-6

9. Acute infections during pregnancy 2- 7

IV Complications of pregnancy

1. Severe early toxicosis 2

2. Bleeding in the first and second half of pregnancy 3-5

3. Late toxicosis.:

dropsy 2 nephropathy I-II-III

degree 3-5-1(

preeclampsia 11

eclampsia 12

4. Combined tokoikoya 9

5. Ph-negative blood 1

6. Ph and ABO-isooensibilia-

7. Miogovodve, 3

9. Breech presentation zЁSH

10. Multiple pregnancy m£Nz

11. Post-term pregnant! - SC

12. Repeated use of medications 1

V. Assessment of the state of the fetus

1. Fetal hypotrophy 10-20

2. Fetal hypoxia 3-8

less than 4.9 mg / day. at 30 over. 34

less than 12.0 mg / day. at 40 weeks fifteen

4. Presence of meconium in amniotic fluid 3

Continuation

B. INTRANATAL PERIOD

From the side of Mia ter and

From the side of the fetus

1. Nephropathy 2. Preclampmia _,.

Premature birth (week of pregnancy): 28 - 30

3. Eclampsia

4. Untimely change

tie amniotic fluid (12 hours or more)

Cardiac arrhythmias (within 30 minutes and

5. Weakness of labor

■helinity

Pathology of the umbilical cord:

6. Quick delivery

dropping out

7. Childbirth, sti-

birth simulation

Pelvic presentation:

validity

8. Clinically narrow pelvis

fruit extraction.

9. Threatening gap

Operational interventions

11. From the side of the placenta 1. "Placenta previa:

caesarean section obstetrical forceps: abdominal

partial

weekends

vacuum extraction

2. Premature

difficult excretion

puff normally dis-

hangers

placenta

General anesthesia in childbirth

tal period, and 8538 deliveries with a favorable outcome. In addition, the results of a study of the fetal condition (ECG, F|KG, ultrasound examination) were used.

The total perinatal mortality for the totality of births in the group as a whole was conditionally taken as I point. Based on this provision, the assessment of points for each risk factor was made on the basis of the calculation of the level of perinatal mortality for the entire set of births and its indicators in women with the presence of one of these factors.

The risk assessment principle was as follows. The probability of the risk of an adverse outcome of pregnancy and childbirth for the fetus and newborn was divided into three degrees: high, medium and low. Each degree of risk was assessed on the basis of the Angar scale and the level of perinatal mortality. The degree of risk of perinatal pathology was considered high for children born with an Apgar score of 0-4 points, medium - 5-7 points and low -8-10 points.

To determine the degree of influence of maternal risk factors on the course of pregnancy and childbirth for the fetus L. S. Persianinov

et al. scoring of all antenatal and intranatal risk factors present in the mother of these children was performed. At the same time, women with a total assessment of prenatal factors of 10 points or more were assigned to the group of high-risk pregnant women, to the group of medium risk - 5 - 9 points, low - up to 4 points.

According to L. S. Persianinov et al. (1976) at the first examination of women (up to 12 weeks of pregnancy), the high-risk group is 18%, and by the end of pregnancy (32 - 38 weeks) increases to 26.4%. According to the literature, the high-risk group of pregnant women is 16.9 - 30% (Hicks, 1992,

Zacutti et al., 1992 and others).

During childbirth, women were distributed according to the degree of risk as follows: with low risk - 42.8%, medium - 30%, high - 27.2%. Perinatal mortality was 1, 4, 20, 0 and .65.2%, respectively. Thus, the proportion of the group of women with low risk during childbirth is decreasing, while the groups of medium and high risk are increasing, respectively. The data obtained by the authors show that risk factors in childbirth have a stronger effect on the level of perinatal mortality compared to those during pregnancy. The combination of high risk factors during pregnancy and childbirth is accompanied by a high rate of perinatal mortality (93.2%). Since the same level of perinatal mortality occurred in pregnant women and parturient women with risk factors estimated at 4 points, this group was classified as high risk factors. The presence of one of these factors in a pregnant woman or a woman in labor requires special attention from an obstetrician-gynecologist and other specialists who monitor her during pregnancy and childbirth. In conclusion, L. S. Persianinov et al. emphasize that the organization of specialized clinics, intense monitoring high-risk pregnant women can significantly reduce perinatal mortality. Thus, intensive dynamic monitoring of one of the high-risk groups made it possible to reduce the level of perinatal mortality by 30% compared with this indicator in a similar group of pregnant women who were under normal supervision.

O. G. Frolova, E. I. Nikolaeva (1976 - 1990) on the basis of a study of the literature, as well as the development of more than 8000 birth histories, individual risk factors were identified. Evaluation of the outcomes of childbirth based on the materials of 2 basic antenatal clinics showed that the group of low-risk pregnant women left 45%, medium risk - 28.6%, high risk - 26.4%. At the same time, perinatal mortality in the high-risk group of pregnant women was 20 times higher than in the low-risk group and 3.5 times higher than in the medium-risk group. During childbirth

the group of women with low risk was 42.8%, medium - 30%, high - 27.2%.

VA Sadauskas et al (1977) also emphasize the importance and expediency of identifying risk factors for the fetus during pregnancy and childbirth.

In each group, from 4 to 11 subgroups were identified, the severity of each factor was assessed according to a five-point system. The applied classification, according to the authors, quite accurately reflects the risk to the fetus in case of diffuse pathology in pregnant women and allows organizing timely and specialized intensive monitoring of the fetal condition. The expediency of identifying high-risk groups is also indicated by other domestic authors. So, A. S. Bergman et al. (1977) emphasize the role of functional and thyroid diagnostics in high-risk pregnant women; (1977). L. S. Persiaminov et al. (1977) point to the role and importance of the use of piperbaric oxygen in pregnant women with high risk factors for the fetus, as a way to reduce perinatal mortality. It is also reported about the role of some extragenital diseases as an increased risk factor (Butkyavichyus S. et al., 1977; Shui-kina E.P., 1976 and others).

Some researchers (Radonov D., 1983) proposes the organization of monitoring of high-risk pregnant women. Firstly, in order to improve the quality of monitoring pregnant women with an increased risk of perinatal pathology, the author developed a special classification based on the etiological principle, according to which 8 groups were distinguished:

Pregnant women with impaired uteroplacental circulation (late toxicosis, hypertension, xipo-nichesmiy nephritis, placenta previa, prostrate interruption);

Causes that adversely affect the fetus (ionization, isoimmunization, infections, chromosomal and gene abnormalities);

Adverse factors from the pelvis, uterus and appendages (narrow pelvis, uterine hypoplasia, tumors);

Incorrect position and presentation of the fetus, multiple pregnancy, multiple pregnancy, fetal growth retardation;

Adverse factors on the part of the mother before and during pregnancy (extragenital diseases, too young or old primiparas who have given birth to 3 or more children, smoking);

Aggravated obstetric history (infertility, death

birth, caesarean section, bleeding, late toxicosis);

Factors related to the social environment (difficult living conditions, insufficient training, etc.);

Psycho-emotional state (unwanted or out-of-wedlock pregnancy, bad psychoclimate iB family and at work). D. Radonov determines the degree of risk by a point system. All intermediate and high risk pregnant women are

hospital.

Secondly, after 20 weeks of pregnancy, all data are recorded on a special gravidogram, which can be used to diagnose early signs of a developing pathology (toxicosis, retarded fetal development, multiple pregnancy, etc.). Thirdly, due to the rapid development in the third trimester, especially in the last month of pregnancy, various complications of the usual weekly monitoring of high-risk pregnant women are not enough. Most of them must be hospitalized, which requires an increase in the number of beds in the "intensified observation unit" - from 1/4 to 1/3 of all beds in the maternity hospital. In this department, a thorough examination of the fetus is carried out (non-stress and oxytocin tests, daily counting of the most pregnant woman 3 times a day for 1 hour of fetal movements, ultrasound scanning, amnioscopy) with fixing the data obtained on a special graph. Thanks to "The implementation of these measures, it was possible to reduce perinatal mortality to 8.9%o in non-dispensary pregnant women - 13.76%o) ■

Domestic scientists have made a great contribution to the development of the problem of high-risk pregnant women. A number of scientists have established a number of risk factors that must be taken into account by a practical obstetrician-gynecologist during pregnancy, and this group of pregnant women often requires a comprehensive examination of the fetal condition using modern hardware and biochemical methods of observation. V. G. Kono-Nikhina (1978), when studying the risk of obstetric pathology in primiparas of various age groups, showed that the young (16-19 years) and older (30 years and older) age of primiparous women is a high risk factor for the development of obstetric pathology . In pregnant women of a young age, compared with the optimal (20-25 years), early and late toxicosis occurs more often (almost twice), especially severe forms of toxicosis, there is a threat of termination of pregnancy twice as often, overpregnancy occurs in 3.2 times more often. In older primiparas, compared with the optimal age, 3 times more often - early and late toxicosis are noted, also 2 times more often the threat of termination of pregnancy, and overpregnancy 6 times, premature and early rupture of amniotic fluid 1.5 times, weakness of birth forces 6.2 times, twice as often noted

There are births with a large fetus and in breech presentation, "pathological blood loss" increases by 2.3 times.

In older primiparas, compared to the optimal age, delivery operations are more often used: obstetric forceps - 3.1 times, vacuum - extraction of the fetus - 2.9 times, caesarean section almost 5 times High incidence of complications during pregnancy and childbirth, especially in primiparous older than 30 years, it is accompanied by a higher frequency of impaired functioning in the fetus and newborn: hypoxia is 6.5 times more common, and the incidence of newborns is 4.5 times higher.

The author believes that the use of the method of intensive monitoring of primiparas of young and older age contributes to a more favorable course of pregnancy and childbirth, and perinatal morbidity and mortality also decrease. According to T.V. Chervyakova et al. (1981) one of the most urgent problems of modern obstetrics is the determination of the tactics of pregnancy and childbirth in women at high risk of perinatal pathology. Addressing these issues will be one of the main ways to improve maternal, perinatal and child morbidity and mortality rates. According to the authors, as a result of the studies carried out, significant progress has been made in the development of criteria for identifying groups and the degree of risk. perinatal pathology.

All studies were carried out in the following 6 main areas: 1) clarification of risk groups for extragenital diseases of the mother; 2) with a complicated course of pregnancy; 3) with anomalies of tribal forces; 4) with the threat of intrauterine and postnatal infection; 5) with the threat of bleeding during childbirth and the early postpartum period. T. V. Cheriakova et al. indicate that as a result of these works, new interesting data have been obtained regarding the pathogenesis and clinic of complications of pregnancy and childbirth in women with various types of extragenital pathology, contraindications for maintaining pregnancy have been identified, indications and contraindications for the use of obstetric operations and anesthesia in childbirth have been clarified, issues have been resolved the use of various types of correlating therapy aimed at maintaining homeostasis in the body of the mother and fetus.

A number of authors offer a set of modern methods for diagnosing risk factors for the fetus during pregnancy. So, in (Study by G. M. Savelieva et al. (1981) in order to identify the degree of risk for the fetus in complicated pregnancy (nephropathy), overmaturity, miscarriage, Rh-sensitization), a complex of modern methods was used to judge feto-llacentral blood circulation

research and the condition of the fetus: cardiomonitoring, ultrasound scanning, the study of volumetric blood flow in the intervillous space of the placenta (OK), the concentration of placental lactogen and estriol in the blood and amniotic fluid: , activity of histidase and urokanyaase) amniotic fluid. The authors examined more than 300 pregnant women.

The conducted studies made it possible to identify a correlative relationship between OK and the appearance of changes in the pathological nature of the studied parameters; initial and pronounced signs of fetal hypoxia according to cardiomonitoring; the possibility of predicting the development of fetal hypoxia in childbirth according to some of the studied physiological and biochemical parameters. So, according to the value of OK, starting from 32 weeks, it is possible to predict the weight of newborns at the time of delivery. A decrease in OC by 30% or more indicates "intrauterine fetal hypoxia. An increase in OC with Rh sensitization above 200 ml / min per 100 g of placental tissue (normally about 100 ml / min, with a placental weight of 500 g) indicates the gigantic size of the placenta and the edematous form of hemolytic disease. . j

Analysis of the results of cardiomonitoring observation made it possible to determine the significance of basal changes, which were expressed as rhythm monotony, basal bradacardia, with iso- or arrhythmia. The authors give a number of the most informative indicators indicating the suffering of the fetus. Therefore, according to the authors, the use of these methods in practice in combination or in isolation makes it possible to more accurately identify the degree of risk to the fetus in a complicated pregnancy and determine the optimal medical tactics. Similar opinions are expressed by other authors. So, N. G. Kosheleva (1981) believes that pregnancy complications should be considered as a risk factor for perinatal pathology. The author points out that the acute forms of late toxicosis are especially unfavorable, while the loss of children in late toxicosis, which developed against the background of hypertension and kidney disease, is especially high.

Particular attention should be paid to the peculiarities of the course of pregnancy in diabetes mellitus. In the presence of a genital infection - endocerkitis, colpitis, or a combination of them, late toxicosis develops in every second or fourth pregnant woman, the threat of termination of pregnancy occurs in every sixth, with cervical colpitis four times more often with genital mikshlazma in the genital tract. Thus, in order to reduce perinatal mortality, it is important not only to diagnose a complicated course of pregnancy, but also to clarify the “background” in which these complications arose. Along

with this, it is necessary to constantly monitor the condition of the intrauterine fetus using modern methods of examination and treatment of the intrauterine fetus.

Of particular importance is the study of risk factors in order to reduce perinatal mortality in a antenatal clinic (Orlean M. Ya. et al., 1981). The authors have identified four risk groups in the conditions of the antenatal clinic: 1) socio-economic; 2) obstetric history; 3) obstetric pathology; 4) concomitant pathology. Rhck was determined by a scoring system from 5 to 45 points. 30 points in one group or 60 points in total is a high risk indicator. These activities made it possible to timely diagnose the early stages of toxicosis (shretoksikoz, vodka) of pregnant women, and their timely hospitalization in hospitals made it possible to reduce the frequency of I-II degree hephropathy. S. E. Rub "ivchik, N. I. Turovich (1981), using a scoring assessment of risk factors in obstetrics, developed by Prof. F. Lyzikov, revealed that the first risk group for the socio-alsh-biological factor was 4% , the second group of the claim - a burdened obstetric history - 17%, the third risk scold - pregnancy complications - 45%, the fourth risk rump - eustragevital pathology - 41% - At the same time, temporary ones with a combination of two or more factors amounted to 4% - In each risk group preventive measures are taken to prevent weakness of labor activity, miscarriage, treatment of subclinical forms of late toxicosis, treatment of Rh-conflict and pregnancy, and in the presence of znstratenital pathology, the presence of pregnant women in the dispensary with a therapist and an obstetrician-gynecologist.

Thus, the identification of pregnant women at risk of pregnancy pathology, timely preventive measures contribute to the reduction of complications in childbirth and perinatal mortality. Some authors (Mikhailenko E. T., Chernena M. Ya., 1982) developed an original method of prenatal preparation of pregnant high-risk groups w> the development of weakness of labor by increasing the endogenous synthesis of prostaglandins, which allowed the authors to reduce the incidence of weakness by 3.5 times labor activity and 2 times reduce the frequency of asphyxia in newborns. L. G. Si-chinav; and et al. (1981) propose to use ultrasound scanning data to determine the degree of risk to the fetus in Rhesus-conflict pregnancy.

At the same time, the optimal time for scanning in pregnant women with isoserological incompatibility of the blood of the mother and fetus should be considered 20–22 weeks, 30–32 weeks and immediately before delivery, which allows diagnosing the initial form of fetal hemolytic disease, determining

degree of risk For the last, which is important for the development of individual tactics for the management of pregnancy and childbirth. Other researchers also propose to use a prenatal diagnostic room more widely to assess the condition of the fetus (Shmorgun F. B., 1981; Zupping E. E. et al., 1981).

At the same time, it is recommended, in addition to cardiomonitoring, "to use biochemical methods - to determine the activity of thermojutabile alkaline phosphatase in the blood serum at the risk of pregnancy (Liivrand V. E. et al., 1981;), the coefficient of estrogen creaginine - as one of the indicators of the state of the intrauterine fetus ( Oinimäe X. V. et al., 1981), the content of steroid hormones and cortisone (Ttamer-mane L. P. et al., 1981); Daupaviete D. O. et al., 1981), to determine the dynamics of the content of placental lactogen in the blood plasma of pregnant pears at risk (Reisher N. A. et al., 1981), as well as the constituents of the symndao-adrenal system (Payu A. Yu. et al., 1981), sex determination is a risk factor based on analysis of X and Y-chromatin in the cells of the tissue of the membranes (Novikov Yu. I. et al., 1981).

N. V. Strizhova et al. (1981) to determine risk groups for late toxicosis of pregnant women, a complex immunodiffusion test is used using standard monospecific test systems for trophoblastic beta-globulin, placental lactogen, placental alpha in the amniotic fluid! - microglobulin, alphag - globulin of the "pregnancy zone", C-reactive protein, fibrinogen, alphag and beta-lipoproteins, as well as tissue antigens of the kidney. E. P. Zaitseva, G. A. Gvozdeva (1981), in order to timely diagnose the true severity of toxicosis, suggest using the immunological reaction to suppress leukocyte adhesion according to Holliday (Halliday., 1972). Postpartum complications are also being studied in women with an increased risk of developing infections (Zak IR, 1981).

There are isolated reports about the peculiarities of the mental development of children born from mothers of high-risk groups. So, M. G. Vyaskova et al. (1981), based on a deep and qualified examination of 40 children of sick mothers (with the involvement of a specialist in psychology and defectology), found that the children of sick mothers differ in the specifics of the development of mental activity, especially speech. The number of children with speech and intellectual pathology in the risk group turned out to be significant (28 out of 40), i.e. 70%. All children with speech and intellectual pathology need special assistance of a different nature - from counseling to education in special schools.

Single works are devoted to modern methods of diagnostics and especially treatment of pregnant women with a high risk of perinatal pathology. So, I. P. Ivanov, T. A. Aksenova

i (1981) note that with a complicated course of pregnancy (toxicoses, anemia, the threat of interruption), the presence of extragenital pathology, heart defects, vegetative-vascular dystonil, hypertension, diseases of the kidneys, endocrine system, etc. (often observed f its npl and central insufficiency, accompanied by hypoxia or fetal hypotrophy.

The degree of fetal suffering depends both on the severity and duration of the underlying disease, and on the severity of pathological changes in the placenta - a violation of its respiratory, transport, and hormonal functions. The success of antenatal disease prevention and treatment of intrauterine fetal suffering is largely determined by the informativeness of methods for diagnosing the condition of the fetus and the timeliness of targeted, highly effective therapy. I. P. Ivanov et al. in terms of dynamic monitoring of the state of the fetus, it is proposed to use phonoelectrocardiotraphy in combination with functional tests and ultrasound scanning, as well as indicators of estriol, placental lactogen, activity of a thermostable isoenzyme, alkaline phosphatase, which reflect the functional activity of the placenta and indirectly allow one to judge the state of the fetus, as well as determining the rate of uteroplacental blood flow by the radioisotope method, indicators of the acid-base state and activity of the dependent and innovatory processes.

The complex of data obtained allows timely and in due volume to carry out pathogenetically substantiated therapy of fetal hypoxia and prevention of fetal hypotrophy.

Of the modern methods of treating hypoxia, I. P. Ivanov et al. point to the widespread hyperbaric oxygenation in combination with medications (cocarbocoilase, ATP, sigetin, complamin, vitamins, etc.) against the background of the treatment of the underlying disease, taking into account the mother-fetal relationship. As a result of such therapy, disturbed indicators of the acid-base state and blood gases, hemodynamics, utero-mammary blood flow, indicators of placental function and fetal condition are normalized.

Foreign researchers also widely use monitoring methods for determining the condition of the fetus in high-risk pregnant groups (Bampson., 1980, Harris et al, 1981, etc.). Teramo (1984) studies show that 2/3 of women whose children die in the perinatal period or suffer from birth asphyxia or diseases in the neonatal period ™ can be detected in advance during pregnancy. Such high-risk women make up 1/3 of the total number of pregnant women. Careful monitoring of a pregnant woman in a antenatal clinic is essential to identify high-risk pregnant women.

The basis for identifying a high-risk pregnant woman is a detailed medical history, including social, medical and obstetrical data, as well as clinical signs and symptoms. The author emphasizes that, along with clinical methods, instrumental examination of the fetus in perinatal centers is necessary.

Tegato (1984) out of a total number of 1695 pregnant women, identified 1 high-risk pregnant woman in 480: history of cesarean section in 1 (60), premature birth (birth of a child weighing less than 2500 g) in history (46), childbirth with congenital | medical history (malformations - 20, neurological defects - 3, miscellaneous - 12) in anamnesis (35), stillbirth (17), chronic diseases (63), chronic urinary tract infections (34), diabetes mellitus ( 10), presence of diabetes mellitus in the family (185), pathological changes in glucose tolerance (21), hypertension (66), uterine bleeding in early pregnancy (IW), first birth over the age of 35 (9).

The author proposes to use cardiotocrgraphy with a decrease in motor activity. It has been shown that the number of movements less than 10 per 12 hours is associated with an increased frequency of fetal asphyxia (Pearson, Weaver, 1976). Next, it is necessary to monitor the growth of the fetus, determine estriol in blood plasma, urine, while it is important to consider what medications a woman takes during this period, since, for example, taking glucocorticoids reduces the production of estriol, it is advisable to analyze estriol every 2 to 3 days, and also determine placental lactsgene, functional tests (oxytocin test).

It is important to note that when using a stress-free test, the author recommends that cardiotocography (CTG) be performed every 1–3 days in preeclampeia, 1–3 times a week in chronic hypertension, every 1–3 days in intrauterine growth retardation, and prenatal effusion. amniotic fluid 1-2 times a day, three hepatosis of pregnant women - daily, with diabetes mellitus, class A according to White's classification weekly at a gestational age of 34-36 weeks, and at a gestational age of 37 weeks - 2-3 times a week, diabetes mellitus, classes A. B, C, D and gestational age 32 - 34 weeks. - every 2nd day., at 35 weeks. - daily, diabetes mellitus, classes F, R at a gestational age of 28 - 34 weeks. - every 2nd day, at 35 weeks. - daily. With changes in the curve of the fetal heart rate and the period of 26 weeks of pregnancy, 1 to 3 times a day.

In a comprehensive monograph by Babson et al. (1979) on the management of high-risk pregnant women and intensive care of the newborn, when determining the degree of risk in the perinatal period, the authors define that such a risk in the perinatal period is the danger of death or

the occurrence of disability during the period of growth and development of a person from the moment of the birth of life to 28 days after birth. At the same time, the authors distinguish between the risk associated with intrauterine development of the fetus and the risk associated with the development of the child after birth. This division allows a better understanding of the factors associated with risk in the perinatal period.

Risk factors related to fetal development

Women who are at high risk of fetal death or injury during pregnancy should be identified. Completely unexpected complications rarely occur in women who have undergone a comprehensive examination and long-term follow-up, during which significant deviations from the norm were detected in a timely manner, appropriate therapy was carried out during pregnancy, and the course of childbirth was predicted.

Here is a list of increased risk factors that contribute to perinatal mortality or morbidity in children. Approximately 10 - 20% of women belong to these groups, and in more than half of the cases, the death of fetuses and newborns is due to the influence of these factors.

1. A history of serious hereditary or family anomalies, such as defective osteogenesis, Down's disease.

2. The birth of the mother herself prematurely or very small for the gestational age at which the birth occurred or cases where the mother's previous birth ended in the birth of a child with the same deviations.

3. Serious congenital anomalies affecting the central nervous system, heart, skeletal system, lung anomalies, as well as general blood diseases, including anemia (hematocrit below 32%).

4. Serious social problems, such as teenage pregnancy, drug addiction, or absence of a father.

5. Absence or late start of medical supervision in the perinatal period.

6. Age under 18 or over 35 years old.

7. Height less than 152.4 cm and weight before pregnancy 20% below or above the weight considered standard for this height.

8. Fifth or subsequent pregnancy, especially if the pregnant woman is over 35 years old.

" 9. Another pregnancy that occurred within 3 months. after the previous I Chey.

| 10. History of long-term infertility or serious drug or hormonal treatment.

11. Teratogenic viral disease in the first 3 months of pregnancy.

12. Stressful conditions, such as severe emotional stress, uncontrollable vomiting of pregnant women, anesthesia, shock, critical situations or a high dose of radiation.

13. Smoking abuse.

14. Complications of pregnancy or childbirth in the past or present, such as toxicosis of pregnancy, premature placental abruption, isoimmunization, polyhydramnios or discharge of amniotic fluid.

15. Multiple pregnancy.

16. Delay in the normal growth of the fetus or a fetus that differs sharply from normal in size.

17. No weight gain or minimal gain.

18. Incorrect position of the fetus, for example, breech presentation, transverse position, unidentified presentation of the fetus at the time of delivery.

19. The gestation period is more than 42 weeks.

Further, the author provides demographic studies on specific complications and the percentage of perinatal mortality for each of the complications, while in more than 60% of cases, fetal death and in 50% of cases, the death of a newborn are associated with complications such as breech presentation, premature detachment, placenta, pregnancy toxicosis , twins and urinary tract infection.

Factors causing an increased risk to the newborn

After delivery, additional environmental factors may increase or decrease the viability of the infant. Babson et al. (1979) point out that the following pre- or post-natal factors place the infant at increased risk and therefore require special treatment and supervision:

1. The presence in the anamnesis of the mother of the above risk factors during pregnancy, especially:

a) belated rupture of the fetal bladder;

b) incorrect presentation of the fetus and childbirth;

c) prolonged, difficult labor or very rapid labor;

d) prolapse of the umbilical cord;

2. Asphyxia of the newborn, assumed on the basis of:

a) fluctuations in the number of fetal heart beats;

b) staining of amniotic fluid with meconium, especially its discharge;

c) fetal acidosis (pH below 7.2);

d) an Apgar score of less than 7, especially if the score is given 5 minutes after birth.

3. Preterm delivery (up to 38 weeks).

4. Late delivery (after 42 weeks) with signs of fetal malnutrition.

5. Babies are too young for this stage of pregnancy (below 5% of the curve).

6. Babies too big for a given gestational age (below 95% of the curve) especially large babies born prematurely.

7. Any breathing disorders or stoppage.

8. Obvious birth defects.

9. Seizures, lameness, or difficulty sucking or swallowing.

10. Bloating and/or vomiting.

11. Anemia (hemoglobin content less than 45%) or hemorrhagic diathesis.

12. Jaundice in the first 24 hours after birth or bilirubin level above 15 mg/100 ml of blood.

1. Initial selection.

2. Selection during a visit to a pregnant antenatal clinic.

3. Selection during childbirth: upon admission to a maternity facility and upon admission to the maternity ward.

4. Evaluation at birth:

a) a newborn

b) mother.

5. Postpartum assessment:

a) a newborn

b) mother.

Pregnant women with identified risk factors are classified as follows: according to the criteria below at each stage:

I. Initial selection Biological and marital factors.

a) high risk:

1. Mother's age is 15 or younger.

2. Mother's age is 35 or older.

3. Excessive obesity.

b) Moderate risk:

1. The age of the mother is from 15 to 19 years.

2. The age of the mother is from 30 to 34 years.

3. Unmarried.

4. Obesity (weight 20% above the standard weight for a given height).

5. Exhaustion (weight less than 45.4 kg.).

6. Small stature (152.4 cm or less).

Obstetric history

A. High risk:

1. Previously diagnosed anomalies of the birth canal:

a) inferiority of the cervix; "

b) abnormal development of the cervix;

c) abnormal development of the uterus.

2. Two or more previous abortions.

3. Intrauterine fetal death or death of a newborn during a previous pregnancy.

4. Two previous premature births or the birth of babies at term, but with insufficient weight (less than 2500 g).

5. Two previous children are excessively large (weighing more than 4000 g).

6. Malignant tumor in the mother.

7. Uterine fibroids (5 cm or more or submucosal localization).

8. Cystic ovaries.

9. Eight or more children.

10. The presence of isoimmunization in a previous child.

11. History of enlampsia.

12. Previous child had:

a) known or suspected genetic or familial anomalies;

b) congenital malformations.

13. A history of complications that required special therapy in the neonatal period, or the birth of a child with a birth injury.

14. Medical indications for termination of a previous pregnancy. B. Moderate risk:

1. Previous preterm birth or the birth of a child at term, but with a small birth weight (less than 2500 g), or abortion.

2. One excessively large child (weight over 4000 g). t>"p^u

3. Previous childbirth ended with surgery: SC

a. caesarean section b. forceps, c. extraction for the pelvic end.

4. Previous prolonged labor or significantly obstructed labor.

5. Narrowed pelvis.

6. Serious emotional problems associated with a previous pregnancy or childbirth.

7. Previous operations on the uterus or cervix.

8. First pregnancy.

9. Number of children from 5 to 8.

10. Primary infertility. ,|

P. Incompatibility according to the ABO system in history.

12. Incorrect presentation of the fetus during previous births.

13. Presence of a history of endometriosis.

14. Pregnancy that occurred after 3 months. or earlier after the last birth.

Medical and surgical history

A. High risk:

1. The average degree of hypertension.

2. Moderate kidney disease.

3. Severe heart disease (II-IV degree of heart failure) or congestion caused by heart failure.

4. Diabetes.

5. Removal of endocrine glands in history.

6. Cytological changes in the cervix.

7. Cardiocellular anemia.

8. Drug addiction or alcoholism.

9. History of tuberculosis or PPD test (diameter greater than 1 cm)

10. Pulmonary disease. ;

11. Malignant tumor.

12. Gastrointestinal disease or liver disease.

13. Previous heart or vascular surgery.

B. Moderate risk.

1. The initial stage of hypertension.

2. Mild kidney disease.

3. Mild heart disease (I degree).

4. The presence of a history of hypertensive consisting of a mild degree at the time! ■ pregnancy.

5. Transferred pyelonephritis.

6. Diabetes (mild).

7. Familial diabetes.

8. Disease of the thyroid gland.

9. Positive results of a serological study.

10. Overuse of drugs.

11. Emotional problems.

12. The presence of sickle-shaped erythrocytes in the blood.

13. Epilepsy.

II. Selection during a visit to a pregnant antenatal clinic” in the prenatal period. ,

Early Pregnancy I

A. High risk: :";"■; : I

1. Absence of an increase in the uterus or its disproportionate increase. I

2, Effect of teratogenic factors:: I

a. radiation; !■:■, ■. ..... - ..... \|

b. infections;

in. chemical agents.

3. Pregnancy complicated by immunization.

4. The need for genetic diagnosis in the antenatal period. 5. Severe anemia (hemoglobin content of 9 g% or less).

B. Moderate risk:

1. Untreated urinary tract infection.

2. Suspicion of an ectopic pregnancy.

3. Suspicion of a failed abortion.

4. Severe indomitable vomiting of a pregnant woman.

5. Positive serological test for gonorrhea.

6. Anemia, not amenable to treatment with iron preparations.

7. Viral disease.

8. Vaginal bleeding.

9. Mild anemia (hemoglobin content from 9 to 10; 9 g%).

Late pregnancy

A. High risk:

1. Absence of an increase in the uterus or its disproportionate increase.

2. Severe anemia (hemoglobin content less than 9 g%).

3. The gestation period is more than 42 1/2 units.

4. Severe preeclampsia.

5. Eclampsia.

6. Breech presentation if normal delivery is planned.

7. Isoimmunization of moderate severity (necessary intrauterine transfusion of blood or complete exchange transfusion of blood to the fetus).

8. Placenta previa.

9. Polyhydramnios or multiple pregnancy.

10. Intrauterine fetal death.

11. Thromboembolic disease.

12. Premature birth (less than 37 weeks of pregnancy).

13. Premature rupture of the amniotic sac (less than 38 weeks of pregnancy).

14. Obstruction of the birth canal caused by a tumor or other causes.

15. Premature detachment of the placenta.

16. Chronic or acute pyelonephritis.

17. Multiple pregnancy.

18. Abnormal reaction to an oxytocin test.

19. Drop in the level of estriol in the urine of a pregnant woman. B. Moderate risk:

1. Hypertension during pregnancy (mild degree).

2. Breech presentation if a caesarean section is planned.

3. Unidentified presentation of the fetus.

4. The need to determine the degree of maturity of the fetus.

5. Post-term pregnancy (41-42.5 weeks).

6. Premature rupture of the membranes (delivery does not occur for more than 12 hours if the gestational age is more than 38 weeks).

7. Induction of labor.

8. Estimated disproportion between the size of the fetus and the pelvis by the time of delivery.

9. Unfixed presentation for 2 weeks. or less before the estimated due date.

A high-risk pregnancy is one in which the risk of illness or death of the mother or newborn before or after birth is greater than normal.

To identify a high-risk pregnancy, a doctor examines a pregnant woman to determine if she has diseases or symptoms that make her or her fetus more likely to get sick or die during pregnancy (risk factors). Risk factors can be assigned points corresponding to the degree of risk. Identification of a high-risk pregnancy is only necessary so that a woman who needs intensive medical care receives it in a timely and complete manner.

A woman with a high-risk pregnancy may be referred to antenatal (perinatal) care (the term "perinatal" refers to events that occur before, during, or after delivery). These departments are usually linked to obstetrics and neonatal intensive care units to provide the highest level of care for the pregnant woman and infant. A doctor often sends a woman to a perinatal care center before giving birth, since early medical supervision greatly reduces the likelihood of pathology or death of the child. A woman is also sent to such a center during childbirth if unexpected complications arise. Typically, the most common reason for referral is a high chance of preterm birth (before 37 weeks), which often occurs if the fluid-filled membranes containing the fetus rupture before it is ready to be born (that is, a condition called preterm rupture of membranes occurs). ). Treatment at a perinatal care center reduces the chance of preterm birth.

In Russia, maternal mortality occurs in 1 out of 2000 births. Its main causes are several diseases and disorders associated with pregnancy and childbirth: the ingress of blood clots into the vessels of the lungs, anesthesia complications, bleeding, infections and complications arising from high blood pressure.

In Russia, the perinatal mortality rate is 17%. Slightly more than half of these cases are stillbirths; in other cases, babies die in the first 28 days after birth. The main causes of these deaths are congenital malformations and prematurity.

Some risk factors are present even before a woman becomes pregnant. Others occur during pregnancy.

Risk factors before pregnancy

Before a woman becomes pregnant, she may already have certain diseases and disorders that increase her risk during pregnancy. In addition, a woman who had complications in a previous pregnancy is more likely to develop the same complications in subsequent pregnancies.

Maternal risk factors

The age of the woman affects the risk of pregnancy. Girls aged 15 years and younger are more likely to develop preeclampsia(a condition during pregnancy in which blood pressure rises, protein appears in the urine, and fluid accumulates in the tissues) and eclampsia (convulsions that are a consequence of preeclampsia). They are also more likely the birth of a child with low body weight or premature. Women aged 35 years and older are more likely to increased blood pressure,diabetes,the presence of fibroids (benign neoplasms) in the uterus and the development of pathology during childbirth. The risk of having a baby with a chromosomal abnormality, such as Down syndrome, increases significantly after the age of 35. If an older pregnant woman is concerned about the possibility of fetal abnormalities, a chorionic villus examination or amniocentesis to determine the chromosome composition of the fetus.

A woman who weighed less than 40 kg before pregnancy is more likely to give birth to an infant with a lower weight than expected according to the gestational age (low weight for gestational age). If a woman gains less than 6.5 kg during pregnancy, the risk of death of the newborn increases to almost 30%. Conversely, an obese woman is more likely to have a very large baby; obesity also increases the risk of developing diabetes and high blood pressure during pregnancy.

A woman less than 152 cm tall often has a reduced pelvis. She also has an increased chance of preterm labor and an underweight newborn.

Complications during a previous pregnancy

If a woman had three consecutive miscarriages (spontaneous abortions) in the first three months of previous pregnancies, then she has a 35% chance of having another miscarriage. Spontaneous abortion is also more likely in women who have previously had a stillbirth between the 4th and 8th months of pregnancy or have had preterm births in previous pregnancies. Before trying to conceive again, a woman who has had a spontaneous abortion is advised to be screened for possible chromosomal or hormonal disorders, structural defects in the uterus or cervix, connective tissue disorders such as systemic lupus erythematosus, or an immune response to the fetus—most often Rhesus incompatibility. -factor. If the cause of spontaneous abortion is established, it can be eliminated.

Stillbirth or neonatal death may be due to fetal chromosomal abnormalities, as well as diabetes mellitus, chronic kidney or blood vessel disease, high blood pressure, or a connective tissue disorder such as systemic lupus erythematosus in the mother or her drug use.

The more premature the previous birth, the greater the risk of preterm birth in subsequent pregnancies. If a woman has a baby weighing less than 1.3 kg, then the probability of premature birth in the next pregnancy is 50%. If intrauterine growth retardation was noted, this complication may recur in the next pregnancy. The woman is being evaluated for disorders that can lead to fetal growth retardation (eg, high blood pressure, kidney disease, overweight, infections); Smoking and alcohol abuse can also lead to impaired fetal development.

If a woman has a baby weighing more than 4.2 kg at birth, she may have diabetes. A woman or baby is more likely to have a spontaneous abortion or die if the woman has this type of diabetes during pregnancy. Pregnant women are tested for its presence by measuring blood sugar (glucose) between the 20th and 28th weeks of pregnancy.

A woman who has had six or more pregnancies is more likely to experience weak labor (labor) during labor and bleeding after delivery due to weakened uterine muscles. Rapid delivery is also possible, which increases the risk of severe uterine bleeding. In addition, such a pregnant woman is more likely to have placenta previa (the location of the placenta in the lower part of the uterus). This condition can cause bleeding and be an indication for a caesarean section because the placenta often overlaps the cervix.

If a woman has a child with a hemolytic disease, then the next newborn has an increased likelihood of the same disease, and the severity of the disease in the previous child determines its severity in the next. This disease develops when a pregnant woman with Rh-negative blood develops a fetus whose blood is Rh-positive (that is, there is incompatibility for the Rh factor), and the mother develops antibodies against the blood of the fetus (sensitization to the Rh factor occurs); these antibodies destroy the fetal red blood cells. In such cases, the blood of both parents is tested. If a father has two genes for Rh-positive blood, then all his children will have Rh-positive blood; if he has only one such gene, then the probability of Rh-positive blood in a child is approximately 50%. This information helps doctors provide proper care for mother and baby in future pregnancies. Usually, the first pregnancy with a fetus with Rh-positive blood does not develop any complications, but contact between the blood of the mother and the child during childbirth causes the mother to produce antibodies against the Rh factor. As a result, there is a danger to subsequent newborns. If, however, after the birth of a child with Rh-positive blood from a mother whose blood is Rh-negative, Rh0-(D)-immunoglobulin is administered, then antibodies against the Rh factor will be destroyed. Due to this, hemolytic diseases of newborns are rare.

A woman who has had preeclampsia or eclampsia is more likely to have it again, especially if the woman has chronically high blood pressure.

If a woman has a child with a genetic disease or a congenital defect, then before a new pregnancy, a genetic examination of the child is usually carried out, and in the case of a stillbirth, both parents. When a new pregnancy occurs, ultrasonography (ultrasound), chorionic villus testing, and amniocentesis are performed to detect abnormalities that are likely to occur again.

Developmental Defects

Defects in the development of a woman's genital organs (eg, doubling of the uterus, weakness or insufficiency of the cervix, which cannot hold a developing fetus) increase the risk of miscarriage. To detect these defects, diagnostic operations, ultrasound or X-ray examination are necessary; if a woman has had repeated spontaneous abortions, these studies are carried out even before the onset of a new pregnancy.

Fibromyomas (benign growths) of the uterus, which are more common in older adults, can increase the chance of preterm birth, complications during childbirth, abnormal presentation of the fetus or placenta, and recurrent miscarriages.

Diseases of a pregnant woman

Some diseases of a pregnant woman can be dangerous for both her and the fetus. The most important of these are chronic high blood pressure, kidney disease, diabetes mellitus, severe heart disease, sickle cell anemia, thyroid disease, systemic lupus erythematosus, and blood clotting disorders.

Diseases in family members

The presence of relatives with mental retardation or other hereditary diseases in the family of the mother or father increases the likelihood of such diseases in the newborn. The tendency to have twins is also common among members of the same family.

Risk factors during pregnancy

Even a healthy pregnant woman can be exposed to adverse factors that increase the likelihood of damage to the fetus or her own health. For example, she may be exposed to teratogenic agents (exposures that cause birth defects) such as radiation, certain chemicals, drugs, and infections, or she may develop a disease or pregnancy-related complication.


Drug exposure and infection

Substances that can cause congenital malformations of the fetus when taken by a woman during pregnancy include alcohol, phenytoin, drugs that counteract the effect of folic acid (lithium drugs, streptomycin, tetracycline, thalidomide). Infections that can lead to birth defects include herpes simplex, viral hepatitis, influenza, paratitis (mumps), rubella, chickenpox, syphilis, listeriosis, toxoplasmosis, Coxsackievirus and cytomegalovirus diseases. At the start of pregnancy, the woman is asked if she has taken any of these medications and has had any of these infections after conception. Of particular concern is smoking, alcohol and drug use during pregnancy.

Smoking- one of the most common bad habits among pregnant women in Russia. Despite awareness of the health risks of smoking, the number of adult women who smoke themselves or live with people who smoke has decreased slightly over the past 20 years, and the number of women who smoke heavily has increased. Smoking among adolescent girls has become significantly more common and exceeds that among adolescent boys.

Although smoking harms both mother and fetus, only about 20% of women who smoke stop smoking during pregnancy. The most common consequence of maternal smoking during pregnancy on the fetus is low birth weight: the more a woman smokes during pregnancy, the lower the baby's weight will be. This effect is more pronounced among older women who smoke, who are more likely to have children with a smaller weight and height. Women who smoke are also more likely to have placental complications, premature rupture of membranes, preterm labor, and postpartum infections. A pregnant woman who does not smoke should avoid exposure to tobacco smoke from other people smoking, as it can similarly harm the fetus.

Congenital malformations of the heart, brain, and face are more common in newborns born to pregnant smokers than to nonsmokers. Maternal smoking may increase the risk of sudden infant death syndrome. In addition, children of smoking mothers have a slight but noticeable lag in growth, intellectual development and behavioral formation. These effects, according to experts, are caused by exposure to carbon monoxide, which reduces the delivery of oxygen to body tissues, and nicotine, which stimulates the release of hormones that narrow the blood vessels of the placenta and uterus.

Alcohol consumption during pregnancy is the leading known cause of congenital malformations. Fetal alcohol syndrome, one of the main consequences of drinking alcohol during pregnancy, occurs in an average of 22 out of 1,000 live births. This condition includes growth retardation before or after birth, facial defects, a small head (microcephaly), likely due to underdevelopment of the brain, and impaired mental development. Mental retardation is a consequence of fetal alcohol syndrome more often than any other known cause. In addition, alcohol can cause other complications, from miscarriage to severe behavioral disorders in the newborn or developing child, such as antisocial behavior and inability to concentrate. These disorders can occur even when the newborn has no obvious physical congenital malformations.

The chance of a spontaneous abortion almost doubles when a woman drinks any form of alcohol during pregnancy, especially if she drinks heavily. Often, birth weight is below normal in those newborns who were born to women who drank alcohol during pregnancy. Newborns whose mothers drank alcohol have an average birth weight of about 1.7 kg, compared with 3 kg for other newborns.

drug use and dependence on them is observed in an increasing number of pregnant women. For example, in the United States, more than five million people, many of whom are women of childbearing age, regularly use marijuana or cocaine.

An inexpensive laboratory test called chromatography can be used to test a woman's urine for heroin, morphine, amphetamines, barbiturates, codeine, cocaine, marijuana, methadone, and phenothiazine. Injecting drug users, that is, drug users who use syringes to use drugs, are at higher risk of developing anemia, infection of the blood (bacteremia) and heart valves (endocarditis), skin abscess, hepatitis, phlebitis, pneumonia, tetanus, and sexually transmitted diseases (in including AIDS). Approximately 75% of newborns with AIDS had mothers who were injection drug addicts or engaged in prostitution. These newborns are also more likely to have other sexually transmitted diseases, hepatitis, and other infections. They are also more likely to be born prematurely or have intrauterine growth retardation.

Main component marijuana, tetrahydrocannabinol, can cross the placenta and affect the fetus. Although there is no definite evidence that marijuana causes birth defects or slows the growth of the fetus in the uterus, some studies show that marijuana use leads to abnormal behavior in the child.

Use cocaine during pregnancy causes dangerous complications for both the mother and the fetus; many women who use cocaine also use other drugs, exacerbating the problem. Cocaine stimulates the central nervous system, acts as a local anesthetic (pain reliever) and constricts blood vessels. Narrowing of the blood vessels leads to a decrease in blood flow, and the fetus does not receive enough oxygen. Reduced delivery of blood and oxygen to the fetus can affect the development of various organs and usually leads to skeletal deformities and narrowing of some parts of the intestine. Neurological and behavioral disorders in children of women who use cocaine include hyperactivity, uncontrollable tremors, and significant learning problems; these disturbances may continue for 5 years or even more.

If a pregnant woman suddenly has high blood pressure, bleeds as a result of placental abruption, or has a stillborn baby for no apparent reason, her urine is usually tested for cocaine. Approximately 31% of women who use cocaine throughout their pregnancy experience preterm labor, 19% of fetal growth retardation, and 15% of premature placental exfoliation. If a woman stops taking cocaine after the first 3 months of pregnancy, the risk of preterm birth and premature placental abruption remains high, but fetal development is usually not impaired.

Diseases

If high blood pressure is first diagnosed when a woman is already pregnant, it is often difficult for a doctor to determine whether the condition is due to pregnancy or has another cause. Treatment of such a disorder during pregnancy is difficult, since therapy, while beneficial to the mother, carries a potential danger to the fetus. At the end of pregnancy, an increase in blood pressure may indicate a serious threat to the mother and fetus and should be quickly eliminated.

If a pregnant woman has had an infectious lesion of the bladder in the past, then a urine test is done at the beginning of pregnancy. If bacteria are found, the doctor prescribes antibiotics to prevent infection from entering the kidneys, which can cause preterm labor and premature rupture of the membranes. Bacterial infections of the vagina during pregnancy can lead to the same consequences. Suppressing the infection with antibiotics reduces the chance of these complications.

The disease, accompanied by an increase in body temperature above 39.4 ° C in the first 3 months of pregnancy, increases the likelihood of spontaneous abortion and the occurrence of defects in the nervous system in a child. An increase in temperature at the end of pregnancy increases the likelihood of preterm birth.

Emergency surgery during pregnancy increases the risk of preterm birth. Many diseases, such as acute appendicitis, acute liver disease (biliary colic), and intestinal obstruction, are more difficult to diagnose during pregnancy because of the natural changes that occur during this time. By the time such a disease is nevertheless diagnosed, it may already be accompanied by the development of severe complications, sometimes leading to the death of a woman.

Complications of pregnancy

Rh factor incompatibility. Mother and fetus may have incompatible blood types. The most common is Rh incompatibility, which can lead to hemolytic disease in the newborn. This disease often develops when the mother's blood is Rh-negative and the baby's blood is Rh-positive due to the father's Rh-positive blood; in this case, the mother develops antibodies against the blood of the fetus. If the pregnant woman's blood is Rh-negative, the presence of antibodies to the fetal blood is checked every 2 months. These antibodies are more likely to form after any bleeding in which maternal and fetal blood may mix, such as after amniocentesis or chorionic villus testing, and during the first 72 hours after delivery. In these cases, and at the 28th week of pregnancy, the woman is injected with Rh0-(D)-immunoglobulin, which combines with the antibodies that have appeared and destroys them.

Bleeding. The most common causes of bleeding in the last 3 months of pregnancy are abnormal placenta previa, premature placental abruption, diseases of the vagina or cervix, such as infection. All women who bleed during this period have an increased risk of miscarriage, severe bleeding, or death during childbirth. An ultrasound (ultrasound), examination of the cervix, and a Pap test can help determine the cause of the bleeding.

Conditions associated with amniotic fluid. Excess amniotic fluid (polyhydramnios) in the membranes surrounding the fetus stretches the uterus and puts pressure on the woman's diaphragm. This complication sometimes leads to respiratory failure in women and premature birth. Excess fluid may occur if a woman has uncontrolled diabetes mellitus, if multiple fetuses develop (multiple pregnancy), if the mother and fetus have incompatible blood types, or if the fetus has congenital malformations, especially esophageal atresia or defects in the nervous system. In about half of the cases, the cause of this complication remains unknown. Lack of amniotic fluid (oligohydramnios) can occur if the fetus has congenital malformations of the urinary tract, intrauterine growth retardation, or intrauterine death of the fetus.

preterm birth. Preterm birth is more likely if the pregnant woman has defects in the structure of the uterus or cervix, bleeding, mental or physical stress, or multiple pregnancies, and if she has previously had uterine surgery. Preterm labor often occurs when the fetus is in an abnormal position (eg, breech presentation), when the placenta separates prematurely from the uterus, when the mother has high blood pressure, or when too much amniotic fluid surrounds the fetus. Pneumonia, kidney infections, and acute appendicitis can also cause preterm labor.

Approximately 30% of women who have preterm labor have a uterine infection even if the membranes do not rupture. Currently, there is no reliable data on the effectiveness of antibiotics in this situation.

Multiple pregnancy. The presence of multiple fetuses in the uterus also increases the chances of fetal birth defects and birth complications.

delayed pregnancy. In a pregnancy that lasts more than 42 weeks, fetal death is 3 times more likely than in a normal pregnancy. To monitor the condition of the fetus, electronic monitoring of cardiac activity and ultrasound (ultrasound) are used.

Underweight newborns

  • A premature baby is a newborn born before 37 weeks of gestation.
  • An underweight infant is a newborn weighing less than 2.3 kg at birth.
  • A small infant for its gestational age is a child with a body weight insufficient for the gestational age. This definition refers to body weight, not height.
  • An infant with developmental delay is a newborn whose development in the uterus was insufficient. This concept applies to both body weight and height. The newborn may be developmentally delayed, small for gestational age, or both.

When it is necessary?

Day hospital- this is a short-term stay department, where a pregnant woman spends several hours a day while performing the necessary procedures (for example, droppers), and after they are completed, she goes home
.

In many conditions, already from the beginning of pregnancy, the doctor can warn that at certain times it will be necessary to go to the hospital. it planned hospitalization. First of all, this applies to women who have various diseases of internal organs, such as arterial hypertension (high blood pressure), diabetes mellitus, heart and kidney diseases. Also, hospitalization is planned for women with miscarriage (previously had 2 or more miscarriages) and other adverse outcomes of previous pregnancies, or if the current pregnancy did not occur naturally, but with the help of hormonal therapy or IVF (in vitro fertilization). Such hospitalization will be for critical periods (dangerous in terms of miscarriage and premature birth) and for the period in which the previous pregnancy was lost.
In the case of planned hospitalization in the hospital, first of all, an additional examination is carried out, which is not possible on an outpatient basis, and prevention of possible complications of pregnancy. The timing of such hospitalizations can be discussed with the doctor in advance, they can be shifted by 2-3 weeks if necessary.

emergency hospitalization recommended for conditions that threaten the health of the expectant mother, the health of the baby and abortion. In this case, refusing hospitalization, a woman may lose her only chance for a successful pregnancy.
The need for hospitalization may arise at any stage of pregnancy, starting from the first days and ending with those cases when childbirth does not occur at the expected time (pregnancy prolongation). Women up to 12 weeks of pregnancy are hospitalized in the gynecology department of the hospital, and after 12 weeks in the department of pathology of pregnant women of the maternity hospital.

High risk pregnant women

1. Severe toxicosis of the 11th half of pregnancy.

2. Pregnancy in women with Rh and ABO - incompatibility.

3. Polyhydramnios.

4. The alleged discrepancy between the size of the fetal head and the mother's pelvis (anatomical narrow pelvis, large fetus, hydrocephalus).

5. Incorrect positions of the fetus (transverse, oblique).

6. Post-term pregnancy.

7. Antenatal fetal death.

8. Threatening premature birth.

11 . Pregnancy and extragenital pathology.

(gestational age 22 weeks or more).

1. Cardiovascular diseases (heart defects, arterial hypertension).


2. Anemia.

3. Diabetes.

4. Pyelonephritis.

5. Thyrotoxicosis.

6. High myopia.

7. Chronic lung diseases (chronic bronchitis, bronchial asthma, history of lung operations).

8. Pregnant women with a gestational age of up to 35 weeks and extragenital pathology are hospitalized in somatic departments of the appropriate profile.

111. Pregnancy and selected risk factors.

1. Pregnancy in a nulliparous 30 years and older.

2. Pregnancy and uterine fibroids.

3. Breech presentation.

4. A scar on the uterus from a previous operation.

5. Multiple pregnancy.

6. Pregnancy in women who gave birth to children with malformations.

7. Pregnant women with intrauterine growth retardation.

8. Threat of abortion.

9. Recurrent miscarriage at critical stages of pregnancy from 22 weeks

10. Anomalies in the development of the fetus.

11. Chronic placental insufficiency.

12. Delayed intrauterine development of the fetus.

13. Pregnancy and uterine fibroids.

14. Termination of pregnancy for medical reasons.

15. Placenta previa.

16. Hepatosis of pregnant women.