Drugs 

Phosphodiesterase type 5 inhibitors: drugs for men

Sexual impotence affects more and more men - especially for residents of megacities. Phosphodiesterase type 5 inhibitors help to cope with the problem. The drugs presented on the domestic market are in great demand.

What are type 5 phosphodiesterase inhibitors?

Sexual life is an important aspect of the relationship between a man and a woman. Violation is becoming a problem, and more recently, even at a relatively young age. Type 5 selective phosphodiesterase inhibitors come to the rescue. This is by blocking the production of the corresponding enzyme.

The choice of drugs in this group is quite wide, but the general effect of phosphodiesterase inhibitors - and. But only if there is sexual arousal. Simply put - the effect will be only when the partner causes desire. Is not . Therapy with such drugs fundamentally solves it, but only acts symptomatically.

Mechanism of action

Each man chooses for himself ways to increase potency and return male strength. Phosphodiesterase inhibitors are considered to be one of the most effective today; their mechanism of action is aimed at blocking the type 5 phosphodiesterase enzyme. Thanks to this effect, the amount of another enzyme increases, which helps to relax the smooth muscles of the arteries of the penis.

The cavernous bodies of the penis are filled with blood and an erection occurs.

After ejaculation, everything returns to the "starting point". Depending on the drug chosen, the exposure time may vary. But at the end of it, the symptom returns.

Therefore, for the next sexual exploits, it is necessary to take a new dose. As an "ambulance" or "rapid response agent", such drugs are perfectly acceptable. But to eliminate the cause of the phenomenon, you need to use complex therapy aimed at treating the underlying ailment.

The best drugs for men

Since we are talking about the representatives of the stronger sex, who in principle do not like, and even more so those who treat sexual dysfunctions, then drugs for a one-time use suit them perfectly. So, we present to your attention the best phosphodiesterase inhibitors. Classification by active substance.

The working substance is sildenafil.

Indications for use:

  • erectile dysfunction (complete or partial);
  • weakening of an erection, which leads to the impossibility of making a full;
  • that occurs even before contact or in the first minutes.

You need to take in a carefully selected dosage, which can only be done by a specialist.

You need to drink one or dissolve one dragee under the tongue (if it is a Soft series) 25-30 minutes before the expected sexual activity. The effect lasts for 4 to 6 hours, depending on the initial indication, individual characteristics and the dose of the drug.

There are a lot of contraindications:

  • serious pathologies of the cardiovascular system, causing a persistent violation of the heart rhythm;
  • eye pathologies in which irreversible processes occur in the retina;
  • renal and hepatic pathologies;
  • during exacerbation of ulcerative and erosive diseases of the gastrointestinal tract;

The daily dose should not exceed 100 mg, and for older men - 50 mg.

Among the side effects, the loss of color perception is especially often noted (it is restored after the medication ceases to work).

Maxigra

A synthetic inhibitor of phosphodiesterase 5 type of Polish production, more affordable, has high efficiency, can be taken from 20 years to old age, as indicated in the instructions for use.

Contraindications are similar to the previous one, since the main component is sildenafil. However, due to the additional components, its aggressive action is less pronounced. In any case, caution should be exercised (consultation with a doctor is required).

The pill is taken an hour before the "romantic date" (best on an empty stomach), the effect lasts for 12 hours. As a result of the reception, the quality of intercourse improves, a stronger erection and full ejaculation are observed.

The medicine has no effect on fertility, therefore, when planning a pregnancy, there are no special indications about taking it. It is not recommended to combine with (especially for heart problems).

Sialil

Active substance - . Helps a man to strengthen an erection and improve the quality and duration of intercourse.

Action time - up to 36 hours. This is the longest period of maintaining an erection for this type of product.

You need to take the medicine 15 minutes before sex. The recommended dose starts at 10 to 20 mg. Additionally, the product is available in the Soft series, in the form of fruit-flavored dragees, which must be absorbed under the tongue. The peculiarity of these sweet pills is that they act faster than traditional ones, which must be taken into account.

  • increased heart rate;
  • increased blood pressure;
  • nausea and vomiting;
  • stool disorders.

Contraindications are standard, however, it is noted that men after suffering strokes and heart attacks are allowed to take the minimum dose, but not earlier than six months after treatment.

The main component is vardenafil. It is used in the treatment of erectile dysfunction, to increase potency, improve the quality and duration of intercourse, enhance the sensations during orgasm.

Available in dosages of 5, 10, 20 and 40 mg of active ingredient per tablet. There is a series of Soft - dragees for sucking under the tongue. They have a pleasant fruity taste and act faster than the usual tablet form. In addition, they can be combined with a small amount of alcohol and fatty foods, which is contraindicated when using the standard form.

Reception classic - 15-30 minutes before sexual activity. The effect lasts for 4-6 hours, depending on the dose and characteristics of the organism, as well as the degree of sexual dysfunction.

Contraindications:

  • individual intolerance to the components of the drug;
  • simultaneous reception with antihypertensive drugs of strong action;
  • low blood pressure;
  • age up to 20 years.

People with impaired renal and liver function, as well as men over 65 years old should limit themselves to a dosage of 5 mg (no more than once a day).

Zidena

Udenafil is a synthetic inhibitor of type 5 phosphodiesterase. The drug is indicated for the treatment of sexual dysfunctions in men of different ages.

An effective dosage is 1 tablet (100 mg) 30-60 minutes before intercourse. maintained for 4-6 hours, depending on the initial symptoms.

Contraindications:

  • adolescence (up to 18 years old);
  • hypersensitivity to the composition of the drug;
  • simultaneous administration with drugs containing nitrates, or nitrogen donors.

With great care and after consulting a doctor, men can be used in such situations:

  • hypotension or uncontrolled hypertension;
  • eye diseases with degenerative phenomena in the retina;
  • after bypass surgery, stroke or heart attack (earlier than six months later);
  • severe liver or kidney failure;
  • blood diseases, especially with an increased prothrombin index (excessive clotting);
  • cardiovascular pathologies in which increased physical activity is contraindicated.