For expectant mother 

What are the diagnostic signs of tuberous sclerosis? Diagnostics of the Sturge-Weber syndrome

Hemangiomas are a type of nevi, i.e. accumulation of a certain type of cells in one area of ​​the skin. In the case of hemangiomas, these are accumulations of cells that form blood capillaries, in fact, accumulations of capillaries, often modified. Due to the fact that these have certain clinical features and risks, and also participate in blood circulation, they are allocated to a separate group of diseases.

Flaming nevus (wine stain, port wine stain)

A wine nevus is a collection of mature dilated capillaries. Outwardly, it looks like a bright pink or crimson spot with clear boundaries. In representatives of the Negroid and Mongoloid populations, the color of the spot may be black. The size of a nevus can be huge and can take up half of the body. The favorite localization of this defect is the back of the neck (Unna's nevus). It can also be located on the face or one half of it, on the mucous membranes. Over time, the nevus can thicken and rise above the surface of the skin.

Flaming nevus is a congenital malformation that occurs both in isolation and in some genetic diseases. For example, with Sturge-Weber syndrome, Klippel-Trenone-Weber syndrome, Rubinstein-Teibi syndrome, Cobb syndrome, Wiedemann-Beckwith syndrome and trisomy 13.

At the same time, a flaming nevus can sometimes be confused with transient spots of the color of red fish (flat hemangioma or simple nevus), which occur in 30-50% of healthy children and, when localized on the face, disappear over time, and when localized on the back of the head and neck, they can disappear and reappear, but covered with hair is almost invisible.

Capillary hemangioma - strawberry nevus

These are bright red spots, clearly demarcated and protruding above the skin. They can be found on any part of the body. These spots appear either in utero or in the first two months after birth.

This type of hemangioma can spontaneously disappear and reappear. By the age of 9, capillary hemangioma disappears without a trace in 95% of children. In this connection, surgical treatment of this type of nevi is not recommended. It is wiser to wait, take good care of this area of ​​the skin in order to avoid infection, ulceration, bleeding.

Cavernous hemangiomas

Cavernous hemangiomas can be combined with strawberry nevus. In this case, they look the same on the outside. With an isolated cavernous hemangioma located deep under the skin, the color of the skin itself either does not change, or has a bluish tint.

Cavernous hemangiomas are also prone to spontaneous self-healing, i.e. may disappear on their own. However, if the localization and development of hemangioma interferes with the development or functioning of any organ, for example, the eye, then medical intervention is necessary. One of the methods of treatment is the introduction of corticosteroids into the hematoma.

Kazabach-Merritt syndrome

This syndrome is characterized by a combination of the presence of a hematoma and a bleeding disorder - a lack of platelets, thrombocytopenia. In this case, hemangiomas are usually located on the skin and tend to grow rapidly. Heavy bleeding is possible.

Disseminated hemangiomatosis

In this condition, many hemangiomas are formed. Both on the skin and in the internal organs. Cutaneous hemangiomas are usually small, red or purple in color.

Localization of hemangiomas in the heart, liver, lungs, nervous system, gastrointestinal tract can disrupt the functioning of the organ and lead to the death of the patient.

If dissemination does not affect internal organs, the hemangioma may spontaneously disappear.

Blue bladder nevus

Blue bladder nevus is a set of cavernous hemangiomas located in the skin, mucous membranes, gastrointestinal tract, as well as in the liver, spleen, and nervous system.

External hemangiomas can be rubbery and painful to palpation. Localization of hemangiomas in the gastrointestinal tract can cause bleeding and anemia.

Klippel-Trenone-Weber syndrome

Klippel-Trenone-Weber syndrome is a combination of a flaming nevus with overgrowth of bone and soft tissue and varicose veins. In this case, these pathologies can be noted not everywhere, but delimited, for example, on one arm or leg, on a part of the body, individual fingers.

With this syndrome, very formidable complications are possible - gangrene, thrombophlebitis, internal bleeding, heart failure, etc.

Hereditary hemorrhagic telangiectasia (Osler-Weber-Randu disease)

This disease is almost always inherited. Externally manifests itself in the form of spots, pimples, arachnid elements of red or purple color, 1-4mm in size. The disease usually manifests itself in adolescence, can be localized on the nose, lips, tongue, face, as well as on any mucous membranes and in many internal organs. The disease is dangerous with the risk of bleeding, especially internal.

Stellate angiomas

Stellate angiomas look like spider veins, ranging in diameter from a few millimeters to several centimeters. When pressed in the center, the entire asterisk turns pale, because the artery that feeds the capillaries of the asterisk is compressed. The most typical localization is the back of the head, forearms, hands, face, ears.

These angiomas occur with an increase in estrogen levels and are observed in almost half of schoolchildren. Easily removed by electrocautery or liquid nitrogen.

Unilateral nevoid telangiectasia.

This disease occurs only in women early in their period or during pregnancy and coincides with an increase in estrogen levels. If telangiectasia appears during pregnancy, then after childbirth it disappears.

Congenital telangiectatic marbled skin (congenital generalized phlebectasia)

Despite the long and scary name, this anomaly does not pose a threat to life. Externally, the affected area of ​​the skin has a marble pattern. Approximately as with physiological marbling of the skin, but more pronounced, which is further enhanced by screaming, crying, and changes in ambient temperature. This pathology is usually localized on the arm, leg or part of the body. Visual manifestations partially or completely disappear with age.

Ataxia-telangiectasia (Louis-Bar syndrome)

This is a hereditary disease that manifests itself in the formation of telangiectasias in a three-year-old child on the conjunctiva, nasal septum, ears, gums, hard palate, chest, popliteal fossa and the place of the elbow bend. At the same time, spots of the color of coffee with milk, graying of hair, symptoms of scleroderma may occur.

Angiokeratomatosis

Angiokeratoma Mibelli- a hereditary disease that resembles a 1-8mm wart, covered with a red, purple or black crust, usually located on the dorsum of the fingers and toes. Localizations are also possible in the projection of the elbow joint and under the knee, less often on the ears, palms and soles. The formation of an angiokeratoma can be triggered by frostbite. You can treat it with cryotherapy.

Shingles angiokeratoma- small papules or nodules of a bluish-red color with a rough surface. As a rule, they are localized on the legs and in adolescence can increase in size. A possible treatment option is surgical excision.

Diffuse trunk angiokeratoma (Fabry disease)

This is a hereditary disease that manifests itself in prepubertal age, when red or black papules up to 3 mm in size appear on the genitals, thighs, legs, groin and near the navel. This is accompanied by fever, severe pain in the arms and legs, blue or redness of the limbs, numbness and tingling in the hands and feet, and clouding of the cornea. If the changes affect the kidneys and heart, then death is very likely.

Anemic nevus

Anemic nevus outwardly resembles vitiligo, leukoderma or nevoid pigmentation defects and is a congenital disease (defect, stigma). Often at birth, it goes unnoticed and is found already in kindergarten in the form of well-defined pale skin spots on the trunk, arms, legs or neck. This disease does not pose a threat to health.

- Neurofibromatosis.
- Tuberous sclerosis.
- Sturge-Weber syndrome.

What is the inheritance type of various neurodermatoses?

- Neurofibromatosis - autosomal dominant.
- Tuberous sclerosis is autosomal dominant.
- Hippel-Lindau syndrome - autosomal dominant.
- "Pigment incontinence" - X-linked dominant.
- Sturge-Weber syndrome - sporadic cases.
- Klippel-Trenoneus-Weber syndrome - sporadic cases.

What is the origin of the term phakomatosis?

The term "phakomatosis" comes from the Greek. phakos (spot) and is used to indicate skin lesions that have a variegated appearance and are delimited from healthy skin. Foci of this type are markers of diseases belonging to this group. In addition to dermatological manifestations, with phakomatosis, hamartomatous damage to tissues of other organs, especially the eyes and the central nervous system, is noted. The term "neurocutaneous syndrome" is used more often.

What are the diagnostic criteria for neurofibromatosis-1?

The presence of two or more of the following:
- spots of the "coffee with milk" type (6 or more spots with a diameter of more than 5 mm before puberty, with a diameter of more than 15 mm after puberty);
- "freckles" (in the groin or axillary areas);
- neurofibromas (2 or more) of any type or 1 plexiform neurofibroma;
- optic nerve glioma;
- Lish nodules (2 or more);
- characteristic bone pathologies (dysplasia of the sphenoid bone of the skull, thinning of the cortical layer of long bones with or without pseudoarthrosis);
- Neurofibromatosis-1 (NF-1) in the next of kin.

How does NF-1 differ from NF-2?

NF-1, classic Recklinghausen's disease, is more widespread (1: 3000-4000 newborns); NF-1 accounts for up to 90% of cases of neurofibromatosis. NF-2 occurs with a frequency of 1: 50,000 newborns and is characterized by the presence of bilateral neuromas of the auditory nerve, intracranial tumors and tumors of the spinal canal, as well as the detection of a similar pathology in close relatives. The occurrence of NF-1 is associated with damage to the 17th chromosome, while NF-2 is based on damage to the 22nd chromosome. In NF-2, cutaneous manifestations and peripheral neuromas are rare. Other subtypes of neurofibromatosis (eg, segmental distribution) have also been described and are significantly less common.

How often do babies have coffee with milk stains?

Almost 2% of newborns of the Negroid race have three spots of the "coffee with milk" type on the skin, while 0.3% of white newborns show only one such spot. The development of neurofibromatosis is more likely in children of the European race with multiple spots like "coffee with milk". In the older age group, a single spot with a diameter of more than 5 mm is observed in 10% of white children and in 25% of children with black skin.

What is the likelihood of a 2-year-old child developing neurofibromatosis with 7 coffee-with-milk spots on the skin of more than 5 mm in diameter?

In such a child, neurofibromatosis (most often type I) will develop with a probability of up to 75%. At annual check-ups, complete dermatologic and ophthalmologic examinations and blood pressure measurements are required.

How often do patients with NF-1 have a family history?

This autosomal dominant disease is characterized by a high incidence of spontaneous mutations; therefore, only 50% of patients have a family history of NF-1 cases.

What are Lish nodules?

These are pigmented hamartomas of the iris. They are not always found in neonates with NF-1, but they appear in 90% of such patients after they reach 6 years of age.

What are the diagnostic signs of tuberous sclerosis?

- Angiofibromas of the face.
- Sublingual or paralingual fibroids.
- "Bumps" of the cortical layer.
- Subependymal nodes or giant cell astrocytomas (histologically confirmed).
- Multiple calcified subependymal nodes protruding into the ventricular cavity (confirmed by x-ray).
- Multiple retinal astrocytomas.

What are the most common initial symptoms of tuberous sclerosis?

Seizures Almost 90% of patients with tuberous sclerosis have seizures of various types. This disease is responsible for 5-10% of infantile seizures. Mental retardation is observed in 60% of such patients.

Why should the term "adenoma of the sebaceous gland" not be used when describing the symptoms of a patient with tuberous sclerosis?

On biopsy, these lesions turn out to be angiofibromas; they have nothing to do with adenomas or sebaceous glands. Rashes of this type occur in almost 75% of patients aged 5-13 years and are usually localized on the face (mainly on the nose). These are monomorphic papular elements of red color; they are often mistaken for acne.

What is tuber in tuberous sclerosis?

These are nodules with a diameter of 1-2 cm, consisting of small stellate neurons and astroglia elements, originating from lines of primitive cells that arise as a result of pathological differentiation. Such nodules can be found in various parts of the cerebral cortex. They are dense to the touch, like small potatoes.

What fabric are the "shagreen" areas made of?

"Shagreen" areas are areas of thickening of the skin that look like a cobblestone pavement. A biopsy determines that these are connective tissue nevi. The term "pebbled" comes from the name of specially processed leather, which is given a relief pattern during the dressing process.

What types of "port wine stains" on the face are most likely associated with CNS pathology or ophthalmic pathology?

Port wine stains can be isolated birthmarks on the skin, and can also be associated with pathological changes in other tissues, especially those underlying: (1) the choroidal vessels of the eye (resulting in glaucoma); (2) leptomeningeal vessels in the brain (resulting in epileptiform seizures; (3) spinal cord (resulting in hemangiomas. A study by Tallman et al. Found that glaucoma and / or seizures were more likely in children with port wine stains) ", which are marked:
1) involvement of the eyelids;
2) symmetrically located "birthmarks";
3) involvement of all three branches of the trigeminal nerve on one side.

If such signs are found, an ophthalmological examination and computed tomography (or NMR tomography) are indicated.

What are the three stages of pigmentary incontinence?

Incontinentia pigmenti - X-linked dominant-type inherited syndrome in which there is a recurrent occurrence of seizures and mental retardation. The male fetus usually dies in utero, therefore 100% of patients are girls.

Stage 1
Vesicular - chains of blisters appear on the skin of the newborn's trunk and limbs, which resolve over several weeks or months. These blisters may resemble the vesicles that form with cold sores. Microscopic examination shows eosinophils in the vesicular fluid.

Stage 2
Verrucous - skin rashes appear at the age of about 3-7 months. The elements of the rash are similar to brown hyperkeratotic warts. The rashes disappear by 1-2 years.

Stage 3
Pigmented - spiral hyperpigmented ("marble cake") linear rashes appear, the elements of which are spots. The rash may disappear over time; by early adolescence or adulthood, only residual hypopigmentation is usually observed (sometimes referred to as stage 4).

Various skin formations such as port wine stains, pigment, scars or acne marks create great discomfort. Dermatologist Linda Kapteine ​​told in an open conversation how to recover from dermatological diseases that were previously considered incurable, and her mother Yanina helped her along with little Ernest.

Is the problem of skin diseases in children urgent?

Dermatological diseases always worry people, especially when we are talking about parents who are worried about skin problems in their children. Patients with various skin diseases come to our clinic, in children it is more often allergic dermatitis, contact dermatitis, and we can diagnose it and carry out therapy. We also have laser equipment available.

The dermatologist needs diagnostic equipment

In the right hand of the dermatologist is a dermatoscope, which all skin doctors have in their pockets. With the help of a special magnifying glass and special light, you can examine any skin formations: moles, warts, vascular formations and at the same time make a diagnosis. The procedure is painless, it is carried out almost contactless.

The second diagnostic technology is siascope. Siascop determines the dermatoscopic picture of education. Using this device, it is possible to determine skin pigmentation both on the upper layers of the skin and deep - the structure of blood vessels.

What made Mommy Janina worry?

"The baby had a hemangioma at two weeks of age. At first it looked like a scuff, but from two months it began to increase. We had a family doctor who sent us to the surgeon for a consultation. Hemangioma is a benign vascular formation, in order to reduce it we were prescribed a special ointment ...

And the second child had one, and the good scenario is that she absorbed herself, "says the mother.

In the case of hemangioma, ointments that contain heart medications are usually advised, because they allow you to heal 60% faster, but there are times when you need to drink medicine.

What did mommy Janina learn during the examination?

In Ernest's case, we saw a hemangioma of small capillaries, there is practically no melanin, but there are cases when they are. This hemangioma is well supplied with blood, collagen structures are minimal, and most likely this hemangioma will resolve. Research is still underway in the world, which is why they appear, but in the case of Ioannina, hemangiomas are considered congenital, and it must be that after using the ointment it will pass.

Hemangiomas, port wine stains - should they be treated?

Vascular hemangiomas and port wine stains can and should be treated. Port wine stains are already a larger cosmetic defect, because often it is on the floor of the face - pink, light pink, dark pink. Capillary malformations of port wine stains live their own lives, they can grow into deep tissues. Vascular lesions are a multidisciplinary problem because they are treated by different doctors, both surgeons and dermatologists. Dermatologists are able to close the blood vessels in the skin, improving the appearance. If the spots are left untreated, scars may develop. At the very beginning, port stains can be treated with laser procedures and you can close them completely, the skin is cleansed, it becomes white and even. Of course, adolescents also come who did not have the opportunity to be treated in childhood precisely because of technology, but then it is possible to get rid of them only up to 80%.

If hemangiomas are located on important, functional structures, then they also need to be treated with laser procedures. In 50% of cases, hemangiomas resolve before 5 years, 70% before 7 years, in 99% before 9 years.

Are there any signs that parents could use to determine if the birthmark is malignant or benign?

Family doctors are highly educated and they can definitely advise a child all the best, and with vascular formations, you need to contact a surgeon. If there are congenital birthmarks, but a different approach is needed here, it all depends on what kind of birthmark it is, it is especially important to pay attention to large birthmarks. The smaller the birthmark, the better the outcome and the greater the likelihood that it will be benign. Most often, it is advised to draw up a birthmark map - in electronic dermoscopy. This means that it is possible to control as the child grows, to observe changes, studying whether there are bad signs. There are not many malignant growths in the world. But you need to check - with a dermatologist or oncologist. Malignant tumors are less common in young children. Here it is necessary to mention ultraviolet radiation, its effect, it is easier for dark-skinned people to get various pigment formations. We take care of children - with protective creams, sunglasses, hats, and growing up to adolescence, he begins to take care of himself. He may want to go to the tanning bed, but unfortunately there is nothing good there.

When do birthmarks need to be removed and at what age. Is it painful?

There are various viral formations that spread rapidly. For example, in developed countries, there are fewer infectious viruses that damage the skin. Warts that definitely need to be treated, and shellfish too. Any neoplasm on the skin of a child should definitely be shown to a doctor.

The procedure was once very painful and the child had to be put to sleep using anesthesia. Now it is possible to use the laughing gas that the child inhales, the central nerve impulses for pain are blocked, the procedure can be carried out calmly, painlessly. As soon as we stop breathing gas, the impulses are restored. The child does not sleep and can go about his business.

Cosmetology Vbeam laser Perfecta ™ is designed for non-invasive vascular surgery - the most effective in the case of port stains and hemangiomas, it can successfully treat acne rashes, warts, dilated vessels, vein problems. Wide application and excellent efficiency.


Birthmarks are colored spots on the skin that are present in babies at birth or appear shortly after birth. More than 10 out of 100 babies have moles.

Moles come in a variety of colors - bright red, pink, brown, and bluish. They can be flat or embossed. Moles are distinguished by color and appearance.

The most common types of moles include:

Coffee with milk stains

These are light brown spots. Up to three of these spots on the body are usually normal. More blemishes may indicate a disorder called neurofibromatosis, a genetic disorder that causes skin tumors.

Hemangiomas

Hemangiomas are flat or slightly raised spots that are bright red or bluish in color. They can appear anywhere on the body, but are common on the face, head, and neck. Hemangiomas are usually present at birth or develop during the first few weeks of life. These birthmarks tend to grow rapidly during the first 12 months of a baby's life. But they stop growing after the first year and then gradually disappear. Hemangiomas can also be found inside the body. There are two types of hemangiomas:

  • Strawberry (strawberry) hemangioma- This type of hemangioma is usually slightly raised above the skin and has a bright red color. This color is associated with the numerous, dilated blood vessels that are close to the skin's surface. These hemangiomas usually disappear on their own before the age of ten (by the age of five in almost half of children). Most do not even require any treatment unless they are located in areas where they could interfere with normal bodily functions, such as around the mouth, nose, eyes, anus, or throat.
  • Cavernous hemangioma- This type of hemangioma is located under the skin. They are more swollen than strawberry hemangiomas and are also bluish in color. This type of hemangioma is less likely to go away on its own. Hemangioma on the face sometimes resembles the symptoms of vascular malformations of the brain, so the doctor may recommend an MRI to make an accurate diagnosis.

"Spots of salmon color"

They are often called "angel kisses" or "stork bites". These harmless pinkish or light red moles can be found anywhere on a baby's body, but most often they appear on the back of the head and neck. They are usually barely visible. No treatment is required for this type of birthmark.

Common moles

Moles appear as dark brown or black spots. Almost everyone has small moles. They usually appear after birth and are actually small groups of colored (pigmented) skin cells.

Mongolian spots

These flat birthmarks on the surface of the skin are blue-gray in color and are often located on the buttocks or at the base of the spine. Mongolian birthmarks are harmless, but they are sometimes mistaken for bruising. Mongolian spots tend to disappear during puberty.

Port wine stains

Port-colored spots are pink, red, or purple spots on the skin. They can be of different sizes and can occur on the face, neck, arms, or legs. Large port-colored patches on the face can be signs of Sturge-Weber syndrome, which can result in seizures and intellectual disabilities.

Congenital hairy nevus

Congenital hairy nevus (giant hairy nevus) is a dark, textured stain that is present from birth. Many of them are covered, at least in part, with hair. They can be very large, cover the abdomen and thighs, or be smaller and multifocal. This birthmark can develop into melanoma at some point in life. The congenital hairy nevus is removed whenever possible. Depending on the size and location of the nevus, it may be necessary to undergo reconstructive surgery in order to achieve a good cosmetic result.

Causes of the appearance of moles

The exact reason for the appearance of moles is unknown.

Risk factors for birthmarks

Factors that increase the likelihood of moles:

  • Hemangiomas are more common in women and premature babies;
  • Mongolian spots are more common among Asians, Africans, Indians and Latinos;
  • Milk coffee stains are more common in African Americans.

Birthmark symptoms

These symptoms, in addition to moles, can be caused by other diseases. Tell your doctor if you have any of these.

Symptoms include:

  • Changes in skin color (skin is lighter or darker than usual);
  • Lump or swelling of the skin;
  • Changes in skin texture;
  • Other damage to the skin.
  • May vary in size and appearance;
  • Most likely present at birth or appearing in the first few weeks or months of life;
  • Commonly found on the face and neck.

Most of the birthmarks, although cosmetically undesirable, are generally harmless. However, hemangiomas and port-wine stains can lead to some complications:

Hemangiomas

  • Open wound or ulcer;
  • Unattractive appearance or dysfunction of nearby organs (such as eyes or mouth);
  • Excessive bleeding after injury;
  • Sudden and rapid growth.

Port wine stains

  • Emotional and social complications;
  • Interference with the function of nearby organs (eg, eyes);
  • Growth problems;
  • Light bleeding.

In rare cases, moles can become cancerous. Any suspicious pigmented lesions should be examined by a physician and monitored or removed.

Diagnostics of birthmarks

The doctor will ask about your symptoms and medical history, and perform a physical exam. Moles are usually diagnosed based on the appearance of the skin. If there is any suspicion of a diagnosis of moles, a biopsy may be ordered for laboratory examination and you may be referred to a dermatologist - a doctor who specializes in skin conditions.

Treatment of birthmarks

Most birthmarks do not require medical attention. Treatment is generally recommended in the following cases:

  • Cosmetically undesirable effect;
  • A mole causes discomfort and complications;
  • A mole has the potential to develop into a more severe condition, such as a tumor (rare).

Treatment options include the following:

  • Corticosteroid drugs are anti-inflammatory drugs that can be given by mouth or by injection. This is the most common treatment for rapidly growing hemangiomas. However, long-term oral corticosteroids have a number of risks, including stunting in children and increased blood sugar;
  • Laser therapy - the laser can be used to prevent the growth of hemangiomas and remove hemangiomas and port-colored stains;
  • Surgery - may be needed to remove pigmented lesions (such as moles) or to remove scars from other treatments
  • Cosmetics - There are many makeup products that effectively cover birthmarks. They are sometimes called corrective and concealing cosmetics.

For those undergoing treatment or observation, regular check-ups with a doctor or dermatologist are important.

Prevention of moles

There are no methods to prevent the appearance of moles. Moles are congenital and present at birth or appear in the first few weeks of life.

33-year-old Katie Piper, who practically lost her face of the sulfuric acid poured on her, took part in a charity project. The TV presenter and model invited four British women with various serious skin problems and helped them transform with makeup.

Women all over the world struggle with self-doubt. This battle against their own complexes can be even more difficult for those who suffer from rosacea, vitiligo, or whose face is covered with scars and scars. British TV presenter Katie Piper, who was doused with sulfuric acid, decided to draw attention to this topic. She invited four women with skin problems to one of London's beauty salons to show how you can change yourself with makeup.

Katie wanted to prove that cosmetics can be used as a tool to boost self-esteem, and not just to hide flaws. “My face is a unique canvas. I can proudly walk without makeup at all, ”Piper said in an interview.

The dramatic transformations of the four heroines of the TV presenter's project will be shown in the documentary "Katie Piper: Face to Face", which will air in mid-April.

Fille: scars

Fille, 23, was injured in a car accident two years ago while volunteering in Ghana. Makeup artists gave the following beauty advice to Phil: “Start your makeup with moisturizer, and apply the foundation with a beauty blender. This will "hammer" the product into the skin and create an even coverage without visible scars or dents. "

Rochelle: Vitiligo

Rochelle was diagnosed with vitiligo when she was just 11 years old. At school, classmates bullied her for white spots on her skin. Now 27-year-old Rochelle prefers not to wear makeup because she doesn't want to hide her natural beauty. But now she is ready to experiment. With the help of the concealer, the makeup artists managed to completely hide the traces of the disease, but Rochelle herself admitted that she was unlikely to be able to do such a make-up for herself every day before leaving the house.

Lisa: Port wine stain

Lisa was born with a unique skin defect called a port wine stain. On the affected area of ​​the face, an accumulation of dilated capillaries appears, forming a red spot, which can be of different sizes and different shades - from light pink and red to dark purple. When the makeup was finished, Lisa was simply stunned. "I'm going to cry. I thought that I hated my face, but now I realized that I could be different, and that's great! ”- she said.

Sanna: rosacea

Sanna was diagnosed with rosacea last September. The girl admitted that the disease affected her relationship with business partners, and now she is very worried about what people think of her. Seeing the results of her transformation, she praised the makeup artists for their excellent work: "Thank you, my red spots on my cheeks have practically disappeared, it's amazing!"

The film will also tell the story of Katie Piper herself. She fell victim to her abusive ex-boyfriend, Daniel Lynch, who hired an accomplice and splashed sulfuric acid in the model's face. As a result of the attack, Piper lost her eyelids, most of her nose, and part of her ear. Her facial skin was eaten away so that the skull was visible. She spent seven weeks in the hospital. After major surgery, Katie remained in a coma for 12 days. Piper lost 38 kg, and for a while she was injected with food through the catheter. Then for two years, 23 hours a day, she wore a special plastic mask to keep scars to a minimum. In total, the girl underwent about 100 operations to restore her facial skin. She now runs a charitable foundation and helps thousands of women with similar problems.