Vaginal tablets and suppositories of Terzhinan for pregnant women - instructions for use, side effects and analogues. Terzhinan during pregnancy - instructions for use. Is it possible Terzhinan during pregnancy, discharge after Terzhinan

While carrying a baby, the female body becomes very vulnerable and many viruses, bacteria try to take advantage of this. Against the background of a weakened immunity, every now and then various diseases may appear. It is quite difficult to resist them for all 9 months and sometimes you have to resort to the help of medications.

Terzhinan during pregnancy has been used for many years to combat vaginitis and has earned the trust of specialists due to its safety.

4 ingredients for complex action

The effect of the drug is due to its composition, which includes 4 of the most important ingredients. To fight female problems, the medicine is helped by:

1. Nystatin. Possesses a pronounced effect aimed at the destruction of fungi of the genus Candida. It effectively inhibits their rapid growth, thereby alleviating the condition.
2. Ternidazole. Belongs to the category of antiseptics. This component is responsible for stopping the development of gardnerella, as well as many other anaerobic bacteria. It is capable of destroying even Trichomonas.
3. Neomycin sulfate. It is a representative of the antibiotics of the aminoglycoside group. It effectively fights against purulent inflammations that form against the background of a violation of the normal microflora of the vagina.
4. Prednisol. Glucocorticosteroid hormone normally produced by the adrenal glands. This substance helps to suppress inflammatory processes in the body. Effective against Klebsiella, Staphylococcus aureus, Enterobacter and other anaerobic bacteria. Relieves redness, relieves itching.

According to statistics, about 70% of pregnant women suffer from an imbalance in the vaginal microflora.

In addition to the main components, suppositories contain auxiliary substances that help maintain the required level of acidity in the vagina and strengthen the protective functions.

What it treats

Only a qualified specialist can prescribe the drug, having assessed the need for treatment with this drug. The instructions for use indicate that Trezhinan gives positive results in the fight against the following diseases:

• bacterial infection by fungi of the genus Candida;
• vaginitis and vaginosis against the background of excessive bacterial growth;
• colpitis;
• endocervicitis;
• trichomoniasis.

In order to avoid infection of the baby from a sick mother when passing through the birth canal, the drug is prescribed as a preventive measure.

Often, the drug can be prescribed as a prophylactic agent to prepare a woman for surgery or artificial termination of pregnancy.

Combination with pregnancy

Many women are frightened by the fact that this drug contains an antibiotic, which can negatively affect the development of the fetus.

Experts, however, claim that it has a local effect, that is, all its components are absorbed and activated directly in the vagina. Only negligible fractions of active substances enter the bloodstream, which allows you not to worry about the effect on the fetus.

In the first trimester of pregnancy, the use of the drug is as undesirable as any other medication. This is due to the high probability of affecting the normal formation of the fetus. A small organism does not yet have a placenta that could protect it. Therefore, the use during this period should be carefully considered by the doctor.

If possible, obstetricians-gynecologists try to replace Terzhinan in the first 12 weeks with other, more gentle drugs.

Starting from the 13th week of an interesting position, many restrictions on the use of medicines are removed from a woman. At this time, the risk of negative effects on the fetus is minimal, so doctors often prescribe Terzhinan. Instructions for use during pregnancy in the 2nd trimester allows it to be used, since the amount of substances that can penetrate the embryo is so small that it cannot have a negative effect on it.

In the last stages of pregnancy, the drug is necessary. To exclude infection of the baby during childbirth. Terzhinan during pregnancy in the 3rd trimester can be prescribed in combination with a special treatment of the vaginal environment in order to normalize the microflora as much as possible.

How to apply correctly

Doctors consider the most optimal time to administer the drug before bedtime. At this moment, the likelihood increases that the medicine will be able to stay in the vagina for a sufficient time directly in contact with the focus of the disease.

The next 30 minutes after the introduction of the candle, the woman is forbidden to get up and move in order to avoid leakage of the product and reduce its effectiveness.

During the use of suppositories, discharge may increase. They become whitish and foamy. This fact indicates the effectiveness of the drug and active cleansing of the vaginal mucosa.

Algorithm for drug administration:

1. Open the packaging.
2. Place the candle in warm boiled water for 30 seconds. During this time, it will become softer and will be able to begin its action in the vagina faster.
3. Lie on your back, bend your knees and inject the pill.

The average course of treatment is about 7-10 days. Although in some cases the doctor can increase it up to 20 days. Such a move will enhance the effect of the drug and avoid recurrence of inflammation.

Thus, Terzhinan is an effective drug that helps not only to overcome thrush and other lesions of the vaginal microflora, but also to increase its resistance.

Some changes taking place in a woman's body, aimed at the preservation and normal development of the fetus, can adversely affect the health of the mother herself. This applies, for example, to the immunodeficiency state accompanying the entire period of gestation, since the immune system perceives the incipient life as foreign and seeks to reject it. As a result, in about 70% of pregnant women, there is an excessive activation of the opportunistic flora, which normally does not cause any pathology. But with suppression of immunity, when the multiplication of microbes, fungi and protozoa on the mucous membranes of the vagina is not limited by anything, diseases can develop that bring inconvenience to the woman, threatening the infection of the child and the appearance of complications of pregnancy. Terzhinan is a universal combined drug used both for prophylaxis and for treatment of emerging diseases caused by opportunistic microorganisms.

How Terzhinan works

The effectiveness of Terzhinan is associated with the spectrum of action of its constituent components.

1.Antifungal antibiotic Nystatin inhibits the growth of fungi of the genus Candida, which cause thrush on the vaginal mucosa.

2. Antiseptic preparation Ternidazole inhibits the reproduction of gardnerella and many varieties of anaerobic bacteria, including Trichomonas.

3. Broad-spectrum antibacterial drug Neomycin sulfate kills both vegetative and dormant forms of a huge number of sensitive aerobic microbes. These include such common microorganisms as staphylococci, Escherichia coli and Pseudomonas aeruginosa, Enterobacter, Klebsiella.

4. Glucocorticosteroid hormone prednisone Normally produced by the human adrenal glands, it quickly reduces local inflammatory manifestations on the vaginal mucosa, relieving redness, swelling, pain and itching.

5. Wheat starch, colloidal silicon dioxide, lactose monohydrate, magnesium stearate - auxiliary substances that help maintain the bactericidal acidity of the vaginal mucosa and protect it from damage.

In what cases is Terzhinan prescribed during pregnancy

Terzhinan is used for the prevention and treatment of diseases caused by microflora that is sensitive to its active ingredients. Its use should begin only after the isolation of specific microorganisms from a smear from the mucous membrane, determination of their sensitivity to antimicrobial and antifungal drugs and a doctor's prescription.

Indications for the appointment of Terzhinan:

• bacterial vaginosis (a condition in which an unlimited growth of conditionally pathogenic flora is recorded, but there are no clinical manifestations yet);
• bacterial vaginitis, colpitis and endocervicitis, including Trichomonas and mixed ones;
• vaginal candidiasis;
• condition after suturing the cervix for ischemic-cervical insufficiency;
• the period of wearing an obstetric unloading pessary to prevent the development of bacterial or fungal vaginitis;
• prophylactic administration before childbirth with suspicion or existing clinic of vaginitis, in order to prevent infection of the fetus at the time of passage through the birth canal of the mother.

In what form is Terzhinan used

Terzhinan is produced and used in the form of vaginal tablets (suppositories). Before use, they must be slightly soaked in water for 30 seconds to accelerate further dissolution. After the introduction, the woman should be in a horizontal position for at least 15 minutes. It is preferable that the use of Terzhinan was postponed to the time immediately before bedtime.

In what doses is Terzhinan prescribed during pregnancy

Terzhinan is prescribed to be inserted deep into the vagina, one tablet per day at approximately the same time. With bacterial inflammatory processes, the course of treatment is 10 days, with candidiasis - up to 20. To prevent the development of vaginosis or vaginitis, it is enough to use it no more than twice a week.

Side effects and contraindications to the use of Terzhinan

The composition of Terzhinan includes low-dose components that are practically not absorbed from the mucous membrane into the systemic circulation. That's why they do not cause side effects in the mother and fetus... In addition, due to the very wide spectrum of antimicrobial and anti-inflammatory action, this drug allows it to be used as a monotherapy, that is, without requiring additional prescription of other drugs. That's why Terzhinan is used in all stages of pregnancy, especially in the second and third trimesters.

Of the side effects, local reactions are possible in the form of increased itching or burning sensation in the first minutes after the introduction of the tablet into the vagina. This is due to increased vulnerability and sensitivity of the inflamed mucous membrane. Cancellation of the drug is not required, since within a few days, against the background of subsiding inflammatory manifestations, the pain disappears.

The only contraindication to the use of Terzhinan is an individual intolerance to any of its components, which manifests itself in the form of an allergic reaction.

Since in the first trimester of pregnancy, the organs and systems of the fetus are actively developing, despite the lack of information about the side systemic action of Terzhinan, the question of its appointment in this period of gestation must be decided by the attending physician.

Reviews on the use of Terzhinan during pregnancy

1. Antonina at the time of 20 weeks of pregnancy, due to the developed threat of miscarriage against the background of isthmic-cervical insufficiency, an operation was performed to suture the cervix. After that, to prevent bacterial complications, she was prescribed a 5-day course of intramuscular injections of the broad-spectrum antibiotic ceftriaxone. A week later, there was an abundant whitish vaginal discharge and itching. The attending physician and laboratory in a smear from the mucous membrane diagnosed thrush.

As directed by Dr. Antonina, she placed Terzhinan vaginal tablets, 1 at night, for 20 days. The itching ceased to bother on the fifth day, the discharge stopped within a week. After a control examination, the gynecologist confirmed the fact of recovery. Since the possible source of the repeated inflammatory process - the suture threads on the cervix - remained, the doctor advised to continue the prophylactic administration of Terzhinan twice a week until delivery. More exacerbations of vaginal infection were not observed in Antonina, the child was born healthy.

2. Have Catherine at the next scheduled examination by an obstetrician at the time of 30 weeks of pregnancy, a high risk of the threat of isthmic-cervical insufficiency was diagnosed due to moderate polyhydramnios and accelerated weight gain of the baby with a tendency to a large fetus. To prevent premature dilatation of the cervix, an intrauterine unloading pessary was placed on her.

Since a preliminary laboratory examination of a vaginal smear indicated signs of developing bacterial vaginosis, the attending physician prescribed a course of treatment with Terzhinan for a period of 7 days daily with the continuation of its prophylactic administration twice a week until the removal of the obstetric ring. At 38 weeks after removal of the pessary, repeated examination of the smear did not reveal any pathology. The baby was born healthy at 39 weeks.

3. Have Svetlana gestational diabetes was diagnosed at 28 weeks gestation. In the period of 30 weeks, examination and laboratory examination of a smear from the vagina did not reveal any pathology. She considered the itching that appears periodically to be a complication of diabetes, so she did not present any complaints to the obstetrician. When regular contractions appeared at 39 weeks, the woman was admitted to the hospital for delivery.

During the initial examination, the doctor on duty diagnosed thrush and treated the vaginal mucosa with antiseptic drugs. Since at least 4 hours remained before delivery, the doctor injected the woman in labor with a Terzhinan vaginal tablet to prevent infection of the fetus. After birth, the infant showed no signs of candidiasis infection.

The drug Terzhinan during pregnancy is taken in the form of suppositories inserted into the vagina for the treatment of diseases caused by the reproduction of pathogenic and opportunistic microorganisms. In 70% of women expecting a baby, the body is experiencing a violation of the optimal balance of the microflora of the genital organs due to changes in the functioning of the hormonal, immune and digestive systems. Terzhinan is prescribed to pregnant women not only for treatment, but also for the prevention of this pathology.

What is Terzhinan

In women, when carrying a child, diseases of a bacterial and fungal nature often occur - vaginitis, candidiasis, latent sexually transmitted infections. Terzhinan suppositories during pregnancy are used to eliminate the unpleasant symptoms of the disease on the genital mucosa and to suppress pathogenic microbes. This combined remedy effectively treats and prevents the development of inflammatory processes.

Active substance

The therapeutic effect of the drug is associated with the content of the components that make up its composition - such as:

• Ternidazole is a substance with antibacterial activity. It is most effective against Trichomonas.
• Nystatin is an antifungal agent that fights candidiasis.
• Neomycin - this substance belongs to the group of aminoglycoside antibiotics that treat purulent complications of infection.
• Prednisolone is a corticosteroid that stops the development of inflammation.

Terzhinan - hormonal or not

The drug contains four active components, one of which belongs to the group of corticosteroids. Prednisolone is a glucocorticoid that rapidly reduces local inflammation of the vaginal mucosa, itching, and burning. The dose of this substance is small - 3 mg per 1 tablet. Terzhinan is classified as a hormonal drug, so its use is prohibited without the permission of a doctor.

What are women prescribed for?

Vaginal suppositories and tablets are safe when taken correctly. This remedy is prescribed for ordinary patients and women expecting a baby. Treatment can be carried out during menstruation. Terzhinan is prescribed for several conditions of the body and for the treatment of such infectious pathologies as:

1. colpitis;
2. vaginitis;
3. purulent discharge from the birth canal;
4. prevention of the development of infection due to surgery;
5. recovery period after treatment of cervical erosion or the installation of a contraceptive coil;
6. preparation for surgery and childbirth;
7. after suturing the cervix due to isthmic-cervical insufficiency;
8. to prevent the development of inflammation while wearing an obstetric unloading pessary;
9. genital ureaplasmosis;
10. trichomonadosis;
11. gardnerellosis;
12. candidiasis;
13. inflammation of the appendages.

Can I use during pregnancy

Women in a position should receive treatment under the supervision of a specialist. The doctor makes an assessment of the patient's condition during a periodic examination and according to the results of laboratory tests. Terzhinan for thrush during pregnancy and for the treatment of other infectious diseases of the genital organs is prescribed according to the same system as for women who are not expecting a baby. Possessing a local effect, the drug practically does not penetrate into the bloodstream, therefore it is not considered dangerous to the fetus, but only in the later stages of gestation.

Terzhinan in early pregnancy

With the vaginal use of Terzhinan during pregnancy, the active components penetrate into the bloodstream in small quantities. In the first three months of bearing a child, it is strictly forbidden to use the drug. This is a period of active formation of the internal organs and systems of the baby's body, and the components that the medicine contains can cause congenital pathologies. To suppress infections in the first trimester, it is recommended to use more gentle means.

In the 2nd trimester

For pregnant women in the second trimester, bans restricting the use of a number of medications are lifted, but antibiotics are not included in this list. Terzhinan contains components that inhibit the activity of microorganisms, but it is approved for use. The drug is available in the form of vaginal tablets, so the amount of substances that can enter the bloodstream will be small and at this stage of the baby's development they will not harm.

In the 3rd trimester

Terzhinan and pregnancy in the third trimester are compatible. It is a very effective drug used for the treatment and prevention of infectious inflammation. To the indications for the appointment of Terzhinan during pregnancy for a long time, the treatment of the birth canal is added immediately before the birth of the child in order to protect the baby from infection during the birth of the baby.

How Terzhinan works

The drug Terzhinan during pregnancy is highly active against a number of pathogens: Trichomonas, Gardnerella, fungi and other bacteria. Local application of the drug protects the epithelial cells of the mucous membranes of the genital organs and maintains the physiological acid-base balance of the internal environment of the vagina. Terzhinan, used during pregnancy, maintains an optimal ratio of beneficial bacteria with opportunistic microorganisms that live on the genitals.

Prednisolone, which is part of the drug, reduces the manifestation of local allergies, the amount of exudate, and inflammation. Ternidazole inhibits the reproduction of the simplest microorganisms (Trichomonas) and some anaerobic bacteria. Neomycin kills staphylococci, Escherichia coli, streptococci, Shigella. Nystatin effectively fights fungus. Microorganisms slowly develop resistance to Terzhinan.

Instructions for use during pregnancy

The ratio of the active substances of the drug is selected so as to cause a synergistic, mutually reinforcing effect on pathogenic microbes, without affecting the natural microflora of the vagina. The medicine is released in the form of yellow vaginal tablets / suppositories. The active ingredients in its composition are contained in the following amounts:

• prednisolone - 3 mg;
• ternidazole - 200 mg;
• neomycin sulfate - 100 mg;
• nystatin - 100 thousand IU.

It is advisable to take Terzhinan immediately after menstruation, but menstruation is not considered a contraindication to the use of the drug. To avoid re-infection with pathogens, the sexual partner must also undergo a course of treatment. The tool is allowed to be used not only by pregnant women, but also by lactating women, because it does not penetrate into breast milk. In addition, it was noted that the drug does not affect the reaction rate.

How to enter

The use of Terzhinan, like other medicines, has certain features. Suppositories are inserted into the vagina, following simple recommendations:

1. Before the introduction, tear the membrane of the drug, place it in boiled water at room temperature for 30 seconds.
2. Insert a wet suppository / tablet deep into the vaginal cavity, lying on your back with your knees bent.
3. After placing the medicine in the birth canal, lie down for 15-30 minutes.
4. It is better to inject the pill before going to bed and not get up after that, so that the melted drug does not flow out when you get up.
5. If your period starts, then continue the course of treatment.

Dosage

The drug does not affect the effectiveness of drugs taken orally, because the dose of active components that have penetrated into the blood is small. Terzhinan during pregnancy is taken intravaginally, one capsule per day. You need to inject the product deep into the vagina, preferably before bedtime. The course of treatment should not exceed 10 days. By the decision of the supervising doctor for complicated vaginitis, the drug is prescribed to be taken for 3 weeks. For preventive purposes, the agent should not be used for more than 6 days.

Side effects of Terzhinan

Only the attending physician can prescribe the drug, because sometimes Terzhinan can cause side effects. In most cases, this reaction is observed in the first days of treatment. Patients feel itching, burning, but gradually all unpleasant symptoms disappear. Nuances:

1. If the side effect of the drug increases, then you should contact a specialist to replace Terzhinan with a similar drug.
2. Suppositories act locally, so overdose is almost impossible.
3. To avoid possible complications, follow your doctor's recommendations.

Discharge after Terzhinan during pregnancy

Sometimes, while taking the drug, a woman may get scared when she sees vaginal discharge. In such a situation, you need to decide why this is happening. Terzhinan is well tolerated during pregnancy, therefore, the main reason for the appearance of fluid is the melting of the substance that makes up the candle. The vaginal mucosa absorbs only a part of the active components, the rest flows out. The liquid preparation can pass from the vagina for several hours. This discharge is not considered a pathology. To avoid staining your laundry, use sanitary napkins during treatment.

Burning sensation from Terginan

At the beginning of treatment with Terzhinan suppositories, the vaginal mucosa may burn slightly and itching may be observed. After two to three days, such unpleasant phenomena should completely disappear against the background of a decrease in the inflammatory process. If the patient has an individual intolerance to any component of the drug, then the listed symptoms will intensify. In this case, she urgently needs to seek help from a doctor, and interrupt the intake of the prescribed remedy.

Contraindications

Terzhinan during pregnancy is absolutely contraindicated to use in the first trimester. During this period, the formation and development of the fetus occurs, and the drug contains active ingredients, even small doses of which can cause significant harm to the child. In severe conditions, when the expected benefit to the mother outweighs the possible risks to the child, the doctor should make the decision on the prescription of the drug.

In addition, contraindications for the use of the drug include individual intolerance to individual components that make up its composition, and allergic reactions. Most cases of burning sensation after taking the drug does not require discontinuation of the drug. This sensation goes away in a few hours. If the unpleasant symptoms intensify and swelling of the mucous membranes develops, then you need to take some remedy for allergies, and do not enter the suppositories anymore.

Terzhinan's price

Prices for this drug practically do not differ in different cities. Vaginal tablets, manufacturer - Bouchard's laboratory, France, package No. 6 cost from 336 to 363 rubles, No. 10 - 435-466 rubles. In addition, there is an opportunity to purchase a medicine from an online pharmacy. Purchases can be received by mail or you can choose to be delivered to the addressee by a courier company.

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